66 -- 66 -- MATRIX ASSISTED LASER DESORPTION IONIZATION (MALDI) TIME-OF-FLIGHT MASS SPECTROMETER SYSTEM

Notice Date

September 21, 2001

Contracting Office

Department of Health and Human Services, Food and Drug Administration, Jefferson Laboratories, National Center for Toxicological Research, Attn: Contracts 3900 NCTR Road, Jefferson, AR, 72079

ZIP Code

72079

Solicitation Number

222-01-2014(P)

Response Due

September 27, 2001

Point of Contact

Sandra Jackson-Davis, Contract Specialist, Phone (870) 543-7469, Fax (870) 543-7990, Email sjackson@nctr.fda.gov

Description

This notice is hereby amended to change the minimum digization from 500 MHz 8 bit digization to 2 GHz 8 bit digization. This modification also amends the acceleration voltage from 30kV acceleration voltage (or better) to 25kV acceleration voltage ( or better).This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation. This is a Request for Proposal (RFP); a written solicitation will not be issued. The Food and Drug Administration is soliciting for a State-of-the-art Matrix Assisted Laser Desorption Ionization (MALDI) Time-of-flight (ToF) Mass Spectrometer. The system shall include reflectron capability, 30kV acceleration voltage (or better), state-of-the-art extraction field and focusing optics, time lag focusing, ultra stable high voltage power supplies, minimum 2GHz 8 bit digization with 256,000 channel (500 us) 16 bit multi channel analyzer, fully automated vacuum system, Nitrogen and NdYag lasers, MS operating system and data interpretation software, Ion-gate for metastable precursor ion selection, collision cell, post acceleration detector for linear mode applications, greater than or equal to 20,000 resolution in reflectron mode, high mass accuracy needs to be less than 10 PPM using an internal standard with 19 inch or greater monitor, optical bench for installation of the second laser (with electronics) and user training. The instrument?s performance will be evaluated based on comparison of a 1:1 (molar ratio) mixture of bovine insulin (m/z 5k) and cytrochrome C (m/z 12.4k), when the instrument has been tuned to maximum resolution on the cytochrome C peak. The instrument that provides the best High Mass performance as judged based on the ratio of the protonated molecules from the two compounds will be judged to have the best performance for bacterial identification purposes. FOB Destination within 120 days after award of a purchase order. Interested offeror?s shall submit descriptive literature along with their cost quotation. Descriptive literature shall be in sufficient detail as to demonstrate that the system offered meets or exceeds the specifications. Award will be made to the vendor who submits a proposal that offer the Best Value to the Government in terms of price and technical ability. The Government may make its decision on the basis of initial quotations received and not have discussions. Therefore each initial quotation should contain the offeror?s best terms from both a price and technical standpoint. This is Request for Proposal number 222-01-2014(P). APPLICABILITY OF FAR PROVISIONS: the following Federal Acquisition Regulation (FAR) provisions and clauses apply to this solicitation and are incorporated by references. FAR 52.212-1 Instruction to Offerors ? Commercial Items. Offer must include a completed copy of Standard Form 1449 and FAR provisions 52.212-3 Offeror Representations and Certifications ? Commercial Items with their offer. FAR provision 52.232-18 Availability of Funds. FAR Provision 52.212-4 Contract Terms and Conditions -- Commercial Items. FAR 52.215-5 Facsimile Quotations. FAR 52.212-5, Contract terms and Conditions Required to Implement Statues or Executive Orders ? Commercial Items, for paragraphs a, b and c, only the following clauses apply to this acquisition: 52.233-3, Protest after Award (31 U.S.C. 3553); 52.203-6, Restrictions on Subcontractor Sales to the Government, with Alternate I (41 U.S.C. 253g and 10 U.S.C. 2402); 52.222-21, Prohibition of Segregated Facilities (FEB 1999); 52.222-26, Equal Opportunity (E. O. 11246); 52.222-35, Affirmative Action for Disabled Veterans and Veterans of the Vietnam Era(38 U.S.C. 4212); 52.222-36, Affirmative Action for Workers with Disabilities (29 U.S.C. 793); 52.222-37, Employment Reports on Disabled Veterans and Veterans of the Vietnam Era (38 U.S.C. 4212); 52.222-19, Child Labor ? Cooperation with Authorities and Remedies (E.O. 13126); 52.225-1, Buy American Act ? Balance of Payments Program ? Supplies (41 U.S.C. 10a-10d) and; 52.232-34, Payment by Electronic Funds Transfer-Other than Central Contractor Registration (31 U.S.C. 3332). Offers are due in this office no later than September 27, 2001, 4:00p.m. The point of contact for this requirement is Sandra Jackson-Davis; telephone (870) 543-7469 and fax number is (870) 543-7990. Submit Offers to the National Center for Toxicological Research, HFT-322, 3900 NCTR Road, Jefferson, AR 72079-9502, Attention Sandra Jackson-Davis. An official authorized to bind the Offeror must sign the terms and conditions of the offer. Offerors that fail to finish required representation and certifications, or reject the terms and conditions of the solicitation, may be excluded from consideration

Web Link

Visit this URL for the latest information about this (http://www.eps.gov/spg/HHS/FDA/NCTR/222-01-2014(P)/listing.html)

Record

Loren Data Corp. 20010925/66SOL003.HTM (D-264 SN50Y3M3)