A -- CANCER INCIDENCE AND MORTALITY IN BLOOD DONORS AND RECIPIENTS: A POPULATION BASED RECORD LINKAGE STUDY

Notice Date

June 26, 2001

Contracting Office

Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Research Contracts Br., 6120 Executive Blvd. EPS Room 608G, Rockville, MD, 20852

ZIP Code

20852

Solicitation Number

N01-CP-21001-38

Response Due

October 14, 2001

Point of Contact

Kim Hall, Contract Specialist, Phone (301) 435-3781, Fax (301) 480-0241, Email kh175r@nih.gov -- Sharon Miller, Contracting Officer, Phone (301) 435-3783, Fax (301) 480-0241, Email sm103r@nih.gov

Description

The Division of Cancer Epidemiology and Genetics and the Division of Cancer Control and Population Sciences, National Cancer Institute, through the Record Linkage Master Agreement Pool, are interested in awarding a master agreement order contract to describe cancer risk in blood donors and recipients, and in assessing if risk in recipients is associated with cancer in donors after adjustment for donors HIV status. Those firms currently in the Master Agreement Pool have already submitted proposals which have determined them to be prequalified to propose for work issued under this mechanism. The purpose of the subject Request for Proposal No. NO1-CP-21001-38, titled "Cancer Incidence and Mortality in Blood Donors and Recipients: A Population-Based Record Linkage Study" is to quantify cancer incidence and mortality in cohorts of blood donors and transfusion recipients whose records are linked to large population-based cancer and vital status registries. The main hypotheses that will be tested are: 1) site-specific cancer risk (including risk of second primary tumors) and mortality patterns in blood donors do not exceed that of the general population; 2) site-specific cancer risk and mortality patterns in blood transfusion recipients do not parallel patterns observed in blood donors; and 3) After accounting for transmission of oncogenic viruses through blood transfusion, excess cancer risk in recipients is not associated with cancer history in the donors whose blood products they received. The North American Industry Classification System (NAICS) code for this project is 541710. The Master Agreement Order RFP will be available electronically. Those interested in obtaining a copy of this RFP should send their e-mail address to Kim L. Hall at kh175r@nih.gov and a copy of the RFP will be forwarded electronically. However, proposals will only be considered from offerors currently in the Master Agreement Pool. Those who are not currently in the Master Agreement Pool and who wish to be considered for inclusion in the pool should consult the Research Contracts Branch website at http://amb.nci.nih.gov under "Current Requests for Proposals" and refer to RFP NO1-CP-01003-13. The duration of the existing Master Agreement Pool is through July 30, 2005. The due date for proposals is March 20 of each year for those interested in being included in the projected annual review. It is anticipated that the Master Agreement Order Request for Proposal will be available at the end of July 2001. Questions should be directed, via facsimile or e-mail, to Kim L. Hall, Contract Specialist, Epidemiology and Support Section, National Cancer Institute, Executive Plaza South, Room 620, Bethesda, MD 20892-7224. No collect calls will be accepted. Phone: (301) 435-3781; Fax: (301) 480-0241; E-mail: kh175r@nih.gov. =09

Web Link

Visit this URL for the latest information about this (http://www.eps.gov/spg/HHS/NIH/RCB/N01-CP-21001-38/listing.html)

Record

Loren Data Corp. 20010628/ASOL003.HTM (D-177 SN50Q0M5)