NATIONAL INSTITUTES OF HEALTH CLINICAL CENTER (NIHCC) OPPORTUNITY FOR COOPERATIVE RESEARCH AND DEVELOPMENT AGREEMENT (CRADA): APPLICATION SPECIFIC ARTIFICIAL NEURAL NETWORK BASED INTELLIGENT COMPUTING SYSTEM FOR ON-LINE AND OFF-LINE QUALITY CONTROL OF A PROCESS.

Notice Date

April 16, 2001

Contracting Office

NIH/TDCB, 6120 Executive Blvd., Suite 450, Rockville, MD 20852

ZIP Code

20852

E-Mail Address

Inquiries and proposals regarding this opportunity (goldsteb@mail.nih.gov)

Description

SUMMARY: The National Institutes of Health Clinical Center (NIHCC) is seeking to enter at least one Cooperative Research and Development Agreement (CRADA). The goal is to develop and implement an application specific artificial neural network based intelligent computing system for on-line and off-line quality control of a process, particularly a medical process, and especially test result production in clinical laboratory automated analyzers. SUPPLEMENTARY INFORMATION: A CRADA is not a grant, and is not a contract for the procurement of goods/services. THE NIHCC IS PROHIBITED FROM TRANSFERRING FUNDS TO A CRADA COLLABORATOR. The CRADA will employ a generalized computational system and method developed earlier at the National Institutes of Health. This technology was developed for the purpose of detecting errors in processes including, but not limited to, data collection in laboratory automated analyzers. The technology is capable of early on-line detection of various types of errors such as bias, precision, and random errors. It may also be developed as an off-line computational component. Theoretical studies have demonstrated significant advantages of this technology over current state-of-the art quality control practice in laboratory instrument quality control monitoring. The primary goal of the CRADA is to use the developed system and method to build practical and useful software and/or hardware components for application in real-world production or assembly process environments such as commercially available laboratory automated analyzers and other appropriate medical or non-medical applications. The described methods and system are the subject of a U.S. patent application filed November 26, 1998 by the Public Health Service on behalf of the Federal Government. Commercialization of new CRADA technology may require obtaining an appropriate PHS license. The collaborator in this endeavor is expected to commit technical personnel commensurate with the level of research activities defined by the CRADA Research Plan. It is anticipated that PHS facilities and/or those of the collaborator will be utilized, as appropriate, for the research activities as defined by the Research Plan. NIHCC anticipates, in addition, that the Collaborator, as appropriate, will provide funding for the project.

Web Link

Technology Transfer Branch, National Cancer Institute, (http://tdcb.nci.nih.gov)

Record

Loren Data Corp. 20010418/SPMSC002.HTM (W-106 SN50J2Y3)