A -- HIV VACCINE DEVELOPMENT RESOURCES

Notice Date

April 13, 2001

Contracting Office

Department of Health and Human Services, National Institutes of Health, National Institutes of Allergy and Infectious Diseases, Contract Management Branch, 6700-B Rockledge Drive, MSC 7612, Bethesda, MD, 20892-7612

ZIP Code

20892-7612

Solicitation Number

NIH-NIAID-DAIDS-02-07

Response Due

July 6, 2001

Point of Contact

Janet Mattson, Contracting Officer, Phone 301-496-0993, Fax 301-480-5253, Email jm32u@nih.gov -- Jacqueline Holden, Senior Contracting Officer, Phone 301-496-7119, Fax 301-402-0972, Email jh55b@nih.gov

E-Mail Address

Janet Mattson (jm32u@nih.gov)

Description

The Preclinical Research Branch (PRB), Vaccine and Prevention Research Program (VPRP), Division of AIDS (DAIDS), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), has a requirement for Vaccine Production. It is anticipated that multiple contracts will be awarded for a period of four years. The development of vaccines to prevent the spread of HIV infection is a national goal of the highest priority. To help accomplish this goal, the Division of AIDS of the National Institute of Allergy and Infectious Diseases plans to establish a pool of prequalified contractors with experience in vaccine development and production. The contract will provide the NIAID with the ability to achieve: 1) process development and GMP production of pilot lots of candidate vaccines; and 2) a rapid response mechanism for funding high priority, targeted developmental research. The NIAID, in consultation with its advisory groups, will establish the priorities for all research and development. VACCINE PRODUCTION. This will require a process development team with the expertise to develop candidate vaccine products including scale-up and production of GLP/GMP lots suitable for human use. In some cases, a Task Order may support work on well-developed products that need only final steps in production and formulation. Other Task Orders may involve very early and iterative steps in the development process and require several years of effort. Four Categories of vaccine concepts will be developed based on (1) Recombinant proteins, (2) DNA vaccines, (3) Vector-based vaccines [viral or bacterial], or (4) Virus-like particles. Offerors may submit proposals based on scale-up and production of any one or more vaccine Categories and will only be considered for work under the Categories selected. RFP NIH-NIAID-02-07 will be available electronically on or about 4/30/01 and may be accessed through the NIAID Contracts Management Branch (CMB) Home Page using the following address and instructions: NIAID CMB Home Page (via the World Wide Web) may be accessed using http://www.niaid.nih.gov/contracts/. Once you are at the NIAID Contracts Page, select "RFPs" and then select "RFP-NIH-NIAID-02-07._ Please note that the RFP for this acquisition has been revised to include only the Work Statement, deliverable and reporting requirements, special requirements and mandatory qualifications, the Technical Evaluation Criteria, and proposal preparation instructions. All information required for the submission of an offer will be contained in the electronic RFP package. Following proposal submission and the initial review process, Offerors comprising the competitive range will be requested to provide additional documentation to the Contracting Officer. Responses to this RFP will be due on 7/6/01. Any responsible Offeror may submit a proposal that will be considered by the Government. This advertisement does not commit the Government to award a contract. Potential for Socioeconomic Program Set-Aside. The work proposed under this contract requires a high level of scientific and technical experience and sophisticated research and production facilities. As such, it is anticipated that only a limited number of institutions will be qualified to perform this work. However, one award will be set aside for small businesses if such companies are technically qualified to perform the work.

Web Link

Visit this URL for the latest information about this (http://www.eps.gov/cgi-bin/WebObjects/EPS.woa/wa/SPF?A=P&P=NIH-NIAID-DAIDS-02-07&L=3465)

Record

Loren Data Corp. 20010417/ASOL014.HTM (D-103 SN50J242)