A -- BIOMARKERS FOR RHEUMATIC AND SKIN DISEASES

Notice Date

January 19, 2001

Contracting Office

National Institutes of Health, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Natcher Building, Room 5AS-13A, 45 Center Drive, MSC 6500, Bethesda, Maryland 20892-6500

ZIP Code

20892-6500

Solicitation Number

NIH-NIAMS-01-05

Response Due

April 4, 2001

Point of Contact

Elizabeth Shanahan, Contracting Officer, 301/594-2543

E-Mail Address

Elizabeth Shanahan (shanahae@mail.nih.gov)

Description

The National Institute of Arthritis and Musculoskeletal and Skin Diseases is seeking proposals from prospective offerors to identify, characterize, and evaluate biochemical/biological markers to assess rheumatic and skin disease risk, onset, progression and response to treatment. For the purpose of this solicitation, biomarkers are defined as cellular, biochemical, molecular, or genetic alterations by which a normal, abnormal, or simply biologic process can be recognized, or monitored. Biomarkers are measurable in biological media, such as in tissues, cells, or fluids. The following describe the technical objectives of this initiative: (1) To conduct translational research in the biology and pathogenesis of rheumatic and skin diseases that directly leads to development, characterization and testing of biomarkers for early disease diagnosis, assessment of disease risk, evaluation of disease course and treatment responses; (2) To conduct early phase evaluation of promising, analytically proven biomarkers or technologies; (3) To develop new biomarkers and biomarkers expression patterns; (4) To develop high throughput, sensitive assay methods for biomarkers for early diagnosis, risk assessment and treatment response; and (5) To conduct early phase clinical/epidemiological studies, e.g., cross-sectional, retrospective, to evaluate predictive value of biomarkers. It is anticipated that one to two cost reimbursement contract awards will be made for a period of three to five years beginning on or about September 30, 2001. The solicitation NIH-NIAMS-BAA-01-05 will be available electronically on or about fifteen days from the date of this notice and may be accessed through the Internet at the following address: http://www.nih.gov/niams/grants/rfp/rfplist.htm. Proposals will be due on or about April 4, 2001. Offerors are responsible for downloading their own copy of the solicitation and amendments and for routinely checking the Internet site for any possible solicitation amendments that may be issued by the Government. All responsible sources may submit proposals which will be considered by the Government. The North American Industrial Classification System (NAICS) code for this acquisition is 541710. This advertisement does not commit the Government to award a contract.*****

Web Link

NIH-NIAMS-01-05 (http://www.nih.gov/niams/grants/rfp/rfplist.htm)

Record

Loren Data Corp. 20010123/ASOL002.HTM (W-019 SN50B2X1)