National Institutes of Environmental Health Sciences, Research Contracts Branch, DERT, P.O. Box 12874, Building 4401, Research Commons, 79 T.W. Alexander Drive, Research Triangle Park, NC 27709

A -- REPRODUCTIVE TOXICOLOGY TEST SYSTEMS SOL N/A (See Item 17) POC Thomas M. Hardee, Contracting Officer (919) 541-0429 WEB: None, None. E-MAIL: None, None. The National Institute of Environmental Health Sciences intends to negotiate with TherImmune Research Corporation of Gaithersburg, Maryland on a sole source basis to expand the efforts described under the Statement of Work of existing contract N01-ES-75409. Specifically, the expanded effort will consist of (1) investigations on behalf of the U.S. Environmental Protection Agency (EPA) in support of its Endocrine Disrupter research initiative and (2) evaluation of possible toxicity in the CNS, the immune system, or the reproductive system in juvenile rats after developmental exposure to combination of AIDS therapies. Authority: 41 U.S.C. 253(c)(1) as set forth in FAR 6.302-1 and HHSAR 306.302-1. Inherent duplication of costs to the Government and unacceptable delays impacting upon the specific studies to be conducted make competition unfeasible. See numbered note 22. Posted 08/03/00 (W-SN482003). (0216)

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