Acquisitions Management Operations Branch, NIAID, 6700-B Rockledge Drive, Room 1130, Bethesda, MD 20892-7605

R -- DEVELOPMENT OF A SPF PIGTAIL MACAQUE BREEDING COLONY SOL RFP-NIAID-DIR-01-51 DUE 082100 POC Karin E. Eddy / Ivan Hernandez, (301) 496-3878 17. The National Institute of Allergy and Infectious Diseases (NIAID), Division of Intramural Research, intends to contract with New Iberia Research Center (NIRC) of the Southwestern Louisiana University for the Maintenance of a Specific Pathogen Free (SPF) Pigtail Macaque Breeding Colony, as a sole source. The NIRC has established a self-perpetuating breeding colony of SPF pigtail macaques (Macaca nemestrina) to ensure the supply of SPF status domestic nonhuman primate subjects of the species required for NIAID research. The program offers healthy pigtail macaque monkeys that are free of specific retroviruses (SIV, SRV-D, STLV-1) and herpes B virus (Cercopithecine herpesvirus 1). The NIRC breeding program continues to support relevant research projects, such as genetic characterization of the colony, which serve to enhance production by insuring that sound breeding and management strategies are implemented. The NIAID requires a minimum of 50 SPF juvenile Pigtail Macaques per year for ongoing NIAID research on the mechanisms of host-specific pathogenesis of SIVagm. The NIRC owns the 361 pigtail macaques involved in an SPF breeding program. For questions about this acquisition, please contact Ivan Hernandez, Contract Specialist, Acquisition Management & Operations Branch, National Institute of Allergy & Infectious Diseases, NIH, 6700-B Rockledge Drive, Rm. 1127, MSC 7605, Bethesda, MD 20892-7605. See number Note 22.***** Posted 06/28/00 (W-SN469466). (0180)

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