Loren Data Corp.

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COMMERCE BUSINESS DAILY ISSUE OF MAY 4,2000 PSA#2593

National Institute of Child Health and Human Development, Contracts Management Branch, 6100 Bldg., Suite 7A07, 6100- Executive Blvd MSC 7510, Bethesda, MD 20892-7510

A -- HORMONAL CONTRACEPTION AND RISK OF HIV TRANSMISSION SOL NIH-NICHD-2000-09 DUE 061600 POC Contact Virginia A. DeSeau/301-496-4611 or Charles W. Grewe/301-496-4611 E-MAIL: click here to contact the Contract Specialist via, vd9t@nih.gov. The National Institute of Child Health and Human Development (NICHD) intends to negotiate with and issue a sole source contract to Family Health International (FHI) for completion of a prospective, observational study of the effect of hormonal contraceptives on the risk of human immunodeficiency virus (HIV) acquisition through heterosexual intercourse. This international study includes recruitment and long-term follow-up of women who are currently seronegative for HIV, but who live in regions with a high incidence of acquisition of HIV. The study includes research to define the role of hormones on associated factors that may affect HIV acquisition or transmission, such as bacterial vaginosis, Herpes Simplex Virus (HSV), Human Papilloma Virus (HPV) and genital HIV shedding. This project, a continuation of a portion of the HIVNET research currently administered by the National Institute of Allergy and Infectious Diseases (NIAID, will now be directly administered by NICHD. The academic/international HIV/contraceptive research infrastructure already in place at FHI, under the established HIV Prevention Trials Network, makes a competitive offering of this project not feasible. This action is conducted under the authority of 41 U.S.C. 253(1), as set forth in FAR 6.302-1. See numbered Note 22. Posted 05/02/00 (W-SN450576). (0123)

Loren Data Corp. http://www.ld.com (SYN# 0008 20000504\A-0008.SOL)


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