National Cancer Institute, Research Contracts Branch, PCPSS, Executive Plaza South, Room 635, Bethesda, Md 20892

A -- PRECLINICAL EVALUATION OF INTERMEDIATE ENDPOINTS AND THEIR MODULATION BY CHEMOPREVENTIVE AGENTS SOL MAA RFP-N01-CN-85052-72 DUE 020100 POC Jacqueline Ballard, Contracting Officer, 301-435-3795 WEB: http://amb.nci.nih.gov/ncics/rfps_published.asp, http://amb.nci.nih.gov/ncics/rfps_published.asp. E-MAIL: Ballard, Jacque (NCI), ballardj@mail.nih.gov. MA RFP NUMBER N01-CN-85052-72, entitled: "Preclinical Evaluation of Intermediate Endpoints and their Modulation by Chemopreventive Agents" AMENDMENT TWO (2) Issue Date: Open Electronic RFP This RFP is amended and is effective January 1, 2000. Please review the Amendment. The RFP may be accessed through the Research Contracts Branch Home Page by using the following Internet address: http://amb.nci.nih.gov/ncics/rfps_published.asp . It is the offeror's responsibility to monitor the above internet site for the release of this solicitation and amendments, if any. POTENTIAL OFFERORS WILL BE RESPONSIBLE FOR DOWNLOADING THEIR OWN COPY OF THE SOLICITATION AND AMENDMENTS. (Hard copies will be available only upon individual request). Due Date: The hour and the date specified for receipt of Offers is changed from August 1 and February 1 to February 1 of every year or the next business day in order to be included in the Annual Technical Review. Proposals received after February 1 will be held until the next annual review. Proposals for furnishing the supplies and/or services in the SCHEDULE will be received at the place specific in, and in the number of copies as amended in ATTACHMENT 3 until 3:00 P.M. EST. Contracting Officer/Contact Point: All references are changed to show Jacqueline Ballard, Contracting Officer, NCI, AMB, PCPSS; 6120 Executive Boulevard, Executive Plaza S., Room 635, Rockville, MD. 20852; Email address: ballardj@mail.nih.gov.; direct phone 301-435-3795; Fax 301-402-8597. Offerors must acknowledge receipt of the amendment by one of the following methods: 1. By requesting a copy of the Standard Form 30 for this amendment and completing the information requested in items 8 and 15, and returning 1 copy of the amendment; (a hard copy of this amendment, including the Standard Form 30 may be requested from Jacqueline Ballard. 2. By acknowledging receipt of this amendment on each copy of the offer submitted; or 3. By separate letter, telegram, or electronic mail which should include a reference to the solicitation and amendment numbers. EXISTING MASTER AGREEMENT HOLDERS NEED NOT APPLY Posted 10/26/99 (W-SN395139). (0299)

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