National Cancer Institute, Research Contracts Branch, PSAS, 6120 Executive Blvd, EPS/Room 638, Bethesda, MD 20892-7227

B -- SPECIAL STUDIES SOL NCI-RFQ-90245-NR DUE 092719 POC Marsha Gorham, Purchasing Agent & Todd Cole, Contracting Officer (301)402-4509 The National Cancer Institute (NCI), Division of Cancer Control and Population Sciences (DCCPS), Office of the Associate Director, Cancer Surveillance Research Program, on procuring a social-epidemiological analyses of behavioral and biologic determinants of African American/white racial disparities in cancer survival from Louisiana State University Medical Center, 433 Bolivar Street, New Orleans, LA 70112. In 1983, the National Cancer Institute began a social-epidemiological study of possible behavioral and biologic determinants of black/white racial disparities in cancer survival. Survival differences in four organ sites were investigated: breast, bladder, colon, and uterine corpus. The collaborative multicenter study focused on population-based samples of new cases from Atlanta, New Orleans and San Francisco/Oakland for 1985-1986. More than thirty-five analyses have been based on the samples since the project started, including histological characteristics of breast carcinoma, treatment plans in stage II node-positive breast cancer, time from symptom recognition to medical consultation, racial survival differences, estrogen receptor status differences, factors associated with stage at diagnosis, social ties and survival difference in dietary intake, etc. Except for Louisiana State University, all other collaborative organizations under the above multicenter study are under the NCI SEER Program. This project will continue to follow cancer patients in New Orleans who were accrued into the Black/White Cancer Survival Study. This will provide follow-up information through December 1999 for all patients for a minimum of 13 years of survival data. Standard procedures for follow-up will be employed, including linkage with state mortality files, updates from hospital tumor registries, physicians, contacts with patients or their family, and tracing patients. Death certificates will be obtained where appropriate. Using this data, a conglomerate of studies using long term survival data will be performed over the next year associated with survival disparity, breast cancer in young women, risk factors in explaining Black/White differences in tumor biology and survival, and race, tumor characteristics and survival. Analyses and reports on these studies shall be completed. As noted, Louisiana State University (LSU) was one of the collaborative organizations for the original Black/White Survival Study conducted in 1983, and it has access to the data and patient based from the study. Furthermore, LSU is the only collaborator that does not operate under the NCI SEER Program. LSU, which operates the Louisiana Tumor Registry, is the only organization in the state which has statutory authority to obtain the required information on cancer patients. LSU also has all the expertise needed to conduct the aforementioned analyses. The Louisiana State University Medical Center is the only source known to the NCI Researcher that has access to the data and participated in the previous Black/White Cancer Survival Study (this allows comparisons with other centers that participated) and can therefore perform the above follow-up and analyses. This notice of intent is not a request for competitive quotation. However, if any interested party believes it can meet the above requirement, it may submit a statement of capabilities. The capability statement and any other furnished information must be in writing and must contain material in sufficient detail to allow NCI to determine if the party can fully meet the requirements. Capability statements must be received in the contracting office by 3:00 p.m., EST on September 27, 1999. If you have any questions, please contact Marsha Gorham, Purchasing Agent on (301)402-4509. A determination by the Government not to compete this proposed requirement based on responses to this notice is solely within the discretion of the Government. Information received shall be considered solely for the purpose of determining whether to conduct a competitive procurement. No collect calls will be accepted. Posted 09/08/99 (W-SN377687). (0251)

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