National Institute on Drug Abuse, Division of Intramural Research, PO Box 5180, Baltimore, MD 21224-0180

68 -- SINGLE NUCLEOTIDE POLYMORPHISM (SNP) ARRAYS SOL NIDA-99-JCA007 DUE 091599 POC Janes C. Amend Tel 410-550-1637 & Fax. 410-550-3146 NIDA/IRP is soliciting proposals for the purchase of human single nucleotide polymorphism (SNP) probe arrays for use with the Affymetrix GeneChip Instrument System in an effort to seek out genes related to drug abuse. The SNP array needs to have 1000 single nucleotide polymorphisms from the human genome represented on the probe array. The 1000 SNP's must be represented on a single probe arrays that must be manufactured by Affymetrix. These probe arrays need to be used in the Affymetrix GeneChip Instrument System; therefore, it is mandatory that the manufacturer of the probe arrays be Affymetrix. The GeneChip instrument consists of a Hewlett-Packard GeneArray Scanner, Fuidics Station, Hybridization oven and a Workstation system. The SNP probe arrays needs to be compatible with all the components of the Affymetrix GeneChip system, as the SNP probe arrays are hybridized with fluorescein-labeled dna target from experimental samples in the hybridiazation oven washed in the fluidics station, scanned in the GeneArray Scanner and subsequently analyzed by the specialized workstation. This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR subpart 12.6, as supplemented with additional information included in the notice. This announcement constitutes the only solicitation. Proposals are being requested and written solicition will not be issued. Solicitation NIDA-99-JCA007 herein is a request for quotation (RFQ). (The solicitaton document, preovisions and clauses herein are those in effect through FAC 90-46). The proposed solicitaton contained herein is restricted to Small Business Concerns. Delivery of the procured biological material shall be FOB DESTINATION, National Institute on Drug Abuse, 5500 Nathan Shock Drive, Baltimore, Maryland #21224. The Government anticipates to award a Firm Fixed-Price contract. The following factors will be used to evaluate offers in descending order of importance: 1) price, 2) technical capability of item offered to meet the government's requirements, 3) past performance. Award will be based on the lowest price, technically acceptable offer from a vendor with a satisfactory past performance record. FAR 52.212-1 Instruction to Offerors-Commercial Items and FAR 52.212-4 Contract Term and Condition Items apples to this acquisition. The offeror shall submit a completed copy of FAR 52.212-3 Offeror Representation and Certifications-Commercial Items with its offer. Direct questions or inquiries referencing the RFQ number by return FAX. (410-550-3146). Proposals shall be received by the NIDA, 5500 Nathan Shock Drive, Baltimore, Maryland #21224 no later than the close business day of the fifteenth day from the date this announcement first appears in the CBD. Offerors are reminded that this announcement constitutes the only solicitation and NO WRITTEN RFQ WILL BE ISSUED. Offeror shall submit a price proposal by return FAX. Posted 08/23/99 (W-SN371021). (0235)

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