National Institute of Child Health and Human Development, Contracts Management Branch, 6100 Bldg., Suite 7A07, 6100- Executive Blvd MSC 7510, Bethesda, MD 20892-7510

A -- THE EPIDEMIOLOGY OF LATE-ONSET GROUP B STREPTOCOCCAL (GBS) SOL SS-NICHD-DESPR-99-22 POC Lynn Salo: 301-435-6962 WEB: National Institutes of Health, http://www.nih.gov. E-MAIL: National Institutes of Health, ls59u@nih.gov. The National Institute of Child Health and Human Development proposes to study the determinants of risk for late-onset Group B Streptococcal Disease (GBS) (onset 7-89 days of age). The proposed study will require 140 cases in a geographically defined population. Baylor College of Medicine, Houston, Texas, has collected 110 cases with an annual occurrence of 30 cases. Because they are accruing approximately 30 cases a year, it is feasible for them to meet our sample size requirements within a one year study period. Any source who thinks they have the ability to meet the required sample size within one year, should prepare a short capability statement. In addition, WESTAT, Inc., Rockville, Maryland, a data coordinating center, has developed the instruments for the study and has developed a system to monitor the adequacy of the data. By contracting with WESTAT, it will allow us to complete the data collection within one year. Any source who thinks they have the instruments and monitoring system in place to allow the data collection within one year, should prepare a short Capability Statement. These statements should be sent to: Mrs. Lynn Salo, Contract Specialist, NICHD/OAM/CMB, Executive Blvd., Room 7A07, 6100 Executive Blvd., MSC 7510, Bethesda, Maryland 20892-7510. If sending by overnight carrier, the last two address lines are: 6100 Executive Blvd., Rockville, Maryland 20852. E-mail and FAX responses are acceptable. Responses are due 45 days from the publication of this announcement. (See Numbered Note 22) Posted 08/16/99 (W-SN368084). (0228)

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