Contracts Management Section, National Institute of Dental and Craniofacial Research, NIH, Natcher Building, Room 4AN-44D, 45 Center Drive MSC 6402, Bethesda, Maryland 20892-6402

A -- STUDY OF DENTAL SEALANT COMPONENTS AND THEIR POTENTIAL RELEASE FOLLOWING CLINICAL USE SOL RFP No. NIH-NIDCR-11-99-1 POC Marion L. Blevins 301 594-0652 The National Institute of Dental and Craniofacial Research intends to negotiate on a sole-source basis with National Medical Services (NMS) to measure levels of bisphenol A (BPA), bisphenol A dimethacrylate (BIS-DMA), and triethylene glycol dimethacrylate (TEGDMA) in salivary samples taken from human subjects before and after placement of dental sealants, and to determine plasma BPA levels following placement of the sealants. NMS is uniquely qualified and capable of expeditiously conducting the study, having already demonstrated validation data for the analytical methods necessary for this study. NMS conducts extensive pharmacological investigations for the development of new drugs and serves as a consultative laboratory for a number of well-known laboratories. The statutory authority is 41 USC 253(c)(1), as set forth in FAR 6.302-1. See Note 22. Posted 11/09/98 (W-SN269679). (0313)

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