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COMMERCE BUSINESS DAILY ISSUE OF SEPTEMBER 1,1998 PSA#2171National Cancer Institute, Research Contracts Branch, PSAS, 6120
Executive Blvd, EPS/Room 638, Bethesda, MD 20892-7227 A -- FRAMINGHAM CANCER FILE UPDATE II SOL RFQ80220(NR) DUE 091698 POC
Marsha Gorham, Purchasing Agent, (301)402-4509 & Todd Cole,
Contracting Officer The Environmental Epidemiology Branch, Division of
Cancer Epidemiology and Genetics, National Cancer Institute plans to
procure the services of the Trustees of Boston University, Boston
University Medical Campus, 80 E. Concord Street, Boston, MA 02118. The
Framingham Heart Study is an ongoing prospective study initiated in
1948 to identify risk factors for cardiovascular disease. Data are
collected biannually from the 5,209 study participants on a variety of
characteristics including weight and other anthropometric measures,
reproductive history, smoking, alcohol ingestion, physical activity,
and medications including exogenous hormones. Extensive diet histories
also were collected from 900 men early in the study. Blood was drawn
at each visit and data on numerous biochemical indices also are
available. The Offspring Study was initiated in 1971 to facilitate
evaluation of genetic hypotheses. NCI initially contracted with Boston
University in 1985 for a computer file of cancer cases diagnosed in
the Framingham Heart Study and Offspring Study. NCI awarded a second
contract to Boston University in 1994 to update the cancer files.
Current files include data on 1,934 cancers diagnosed in cohort members
and 684 cancers diagnosed among the offspring. These data have been
used collaboratively by NCI, Framingham and Boston University staff to
evaluate relationships of body size, alcohol ingestion, physical
activity, and bone density to breast cancer risk, parental age at birth
to prostate cancer risk, and physical activity to colon cancer risk.
The Framingham Heart Study and Offspring Study contain a wealth of
information on exposures potentially related to cancer. The usefulness
of these data increases as the number of cancer diagnoses grows. The
Government's Framingham Cancer File Update is necessary so the
usefulness of the Framingham Heart Study and the Offspring Study to
evaluate etiologic hypotheses for cancer remains current and up-to-date
since 1994. Since Boston University has all rights to the data on
cancer among members of the Framingham Heart Study and Offspring Study,
it is the only source known to NCI that can meet the requirements of
updating the data that NCI already has available from the Framingham
studies. If any interested party believes it can perform the above work
and maintain the reliability of all data, it may submit a statement of
capabilities. The statement of capabilities and any other information
furnished must be in writing and must contain material in sufficient
detail to allow NCI to determine if the party can perform this
requirement. Capability statements must be received in the contracting
office by 3:00 p.m. EST, on September 16, 1998. If you have any
questions, please contact Marsha Gorham, Purchasing Agent on (301)
402-4509. A determination by the Government not to compete this
proposed requirement based upon responses to this notice is solely
within the discretion of the Government. Information received will be
considered solely for the purpose of determining whether to conduct a
competitive procurement. Posted 08/28/98 (W-SN243476). (0240) Loren Data Corp. http://www.ld.com (SYN# 0009 19980901\A-0009.SOL)
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