DHHS, PHS, CDC, NIOSH, ALOSH, 1095 Willowdale Rd., Morgantown, WV 26505-2888

66 -- MURINE WHOLE BODY PLETHYSMOGRAPH SYSTEM SOL Reference RQ98-038 DUE 082798 POC Brenda Goodwin, 304/285-5882/Contracting Officer, Rex S. Wolfe, 304/285-5883 The National Institute for Occupational Safety and Health (NIOSH) in Morgantown, WV has a requirement to purchase a plethysmographic system that will allow ease in assessing airway reactivity in conscious, unrestrained rodents. These methods minimize both physiologic reactance and animal preparation time. This non-invasive technique allows for long term (>24 hours) and/or repeated measurements from the same group of animals. The Murine Whole Body Plethysmograph System to be purchased is comprised of the following items: Unrestrained Single Chamber (PLY3211); Restrained Whole Body Chamber (PLY3511); Modular Accessory Unit (MAX1420); Strain Gauge Preamp (MAX2270); Transducer (TRD5100); 400MHz, Pentium II, 19" monitor JAZ, ADA (PC-0200); SFT1814; SFT1410; Bias Flow Box (PLY1040) and Aerosolization System (AUT5005). The Health Effects Laboratories Division, NIOSH has already established respiratory models using Buxco systems and this plethysmographic system could be operated using some of the same hardware/ software and training time could also be minimized. It is believed that Buxco Electronics, Inc., Sharon, CT is only source for for the plethysmograph system described above. If there are other sources capable of providing a similar system, they are invited to submit appropriate documentation, literature and references to Brenda L. Goodwin, Reference: RQ98-037, DHHS, PHS, CDC, NIOSH, ALOSH, 1095 Willowdale Road, Morgantown, WV 26505. If no organizations respond and demonstrate their capabilities within seven (7) days after posting of this notice, the Government intends to negotiate on a sole source basis with Buxco Electronics, Inc. This notice is issued for informational purposes. Posted 08/14/98 (W-SN237255). (0226)

Loren Data Corp. http://www.ld.com (SYN# 0351 19980818\66-0017.SOL)