DEVELOPMENTS AT NIST Researchers at the National Institute of Standards and Technology (NIST) have developed a number of new devices and methods involving a variety of technologies. In certain cases other parties have participated in the development of these technologies. NIST may enter into a Cooperative Research and Development Agreement (CRADA) with interested parties to perform further research on the invention for purposes of commercialization. NIST may grant CRADA Partners an option to negotiate for exclusive licenses to any jointly owned inventions which arise from the CRADA as well as an option to negotiate for exclusive royalty-bearing licenses for NIST employee inventions which arise from the CRADA. Anyone interested in the further development of any of these technologies or in applying for a license to commercialize these technologies shall send a written request for further information, referencing the NIST Docket Number and Title to: National Institute of Standards and Technology, Industrial Partnerships Program, Building 820, Room 213, Gaithersburg, Maryland 20899; Telecopy: 301-869-2751. This is not an announcement of a contract action or a grant. NIST DOCKET NUMBER: 97-046PA, Title: Efficient Drift Correction Procedure, Description: The invention describes a numerical methodology to diagnose the low frequency noise-drift-encountered in an analytical experiment, using repeated measurements and a model of the instrument response. The invention is available for commercial use without a license. DOCKET NUMBER: 97-048PA, Title: Optical Frequency Shifter With Optical Gain, Description: This invention is jointly owned by the U. S. Government, as represented by the Secretary of Commerce, and the University of Colorado. A broadband optical frequency comb generator consists of an efficient electro-optic phase modulator within an optical cavity. With an appropriate choice of cavity length, an optical comb extending over a TeraHertz is produced. A closely-spaced additional mirror on the output side is used to resonantly out-couple a selected order of sideband. The invention realizes an optical gain within the cavity by using the modulator crystal as an Optical Parametric Amplifier, pumping it with a wavelength near 1/2 the wavelength being modulated. In this way optical gain can reduce the net optical loss of the comb generator cavity and extend the comb spectral coverage by a large factor. When the gain is sufficiently large, injection-locked oscillation and a dramatic further spectral broadening occurs, leading to a width somewhat comparable with the input optical frequency itself. The method of Telle and Hansch is used to relate the optical frequency to the comb frequency spacing, that is, to use the disclosed modulator technology to synthesize an optical frequency from a microwave standard. NIST DOCKET NUMBER: 98-001PA, Title: Chemically Reversible Gels for Electrophoretic Separations of DNA and Proteins, Description: The technology describes the formulations and applications of reversible electrophoresis gels based on a carbohydrate polymer. The technology is unique in that it describes the conditions for the use of gellan gum for the formation of low concentration electrophoresis gels that are chemically reversible for the recovery of DNA and proteins. These chemical conditions are based on ionic environment, pH(using diamines for reversible chemical cross-linking) and by redox state (using reversible disulfide cross links.) NIST DOCKET NUMBER: 98-006PA, Title: Novel Methods and Compositions for the Preparation of Silyl Derivatives of Resins, Description: The disclosure describes novel silanated resins prepared by exchange reactions involving hydroxylated, carboxylated and other functionalized monomers and oligomers with several silane agents. The novel resins exhibit strong affinity for glass substrates and yield strong, tough polymers. WEB: NIST Contracts Homepage, http://www.nist.gov/admin/od/contract/contract.htm. E-MAIL: NIST Contracts Office, Contract@nist.gov. Posted 06/25/98

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