National Institute of Child Health and Human Development, Contracts Management Branch, 6100 Bldg., Suite 7A07, 6100- Executive Blvd MSC 7510, Bethesda, MD 20892-7510

A -- FOLLOW-UP OF AN ADULT COHORT WITH A KNOWN INFANT FEEDING HISTORY SOL NICHD-CRMC-HD-8-3279 DUE 051298 POC Mya N. Hlaing, Contracting Officer (301)496-4611 WEB: National Institutes of Health, http://www.nih.gov. E-MAIL: National Institutes of Health, mh89m@nih.gov. The National Institute of Child Health and Human Development (NICHD) plans to award a contract to the University of Iowa Hospital, using other than full and open competition to conduct a follow-up of an adult cohort with a known infant feeding history. The determination to use other than full and open competition was made in accordance with 41 USC 253 (c)(1) and is based upon the following factors: 1) The proposed study is a retrospective cohort study, performed by following up on subjects from a series of non-randomized clinical trials performed during 1965-1978 in Iowa, for the purpose of determining if exposure to soy formula in infancy may be associated with adverse outcomes in early adulthood. (See Numbered Note 22). The accomplishments expected under the proposed action are: 1) To locate the great majority of the subjects included in the original cohorts exposed to soy-based and cow milk-based formula during the original clinical trial; 2) To ask for their cooperation in a new study which will request information about their medical histories; 3) To organize this information and provide it to a group of epidemiologists who will compare the incidence and distribution of selected outcomes among the exposure groups. The purpose of this synopsis is to determine whether there are other sources with the above capabilities to perform the work described above. Capability statements should be submitted with 45 days of the publication of this synopsis to Ms. Mya N. Hlaing, Contracting Officer, CMB, NICHD,NIH, 6100 Executive Building, MSC 7510, Bethesda, Maryland 20892-7510. Phone number: (301)496-4611 and FAX number : (301)402-3676 (See Numbered Note 22) (0085)

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