U. S. Environmental Protection Agency, Contracts Management Division (MD-33), Research Triangle Park, NC 27711

A -- SOURCE TO DOSE EXPOSURE MODELING SOL NERL/HEASD/001 DUE 051598 POC Shari Pricer, 919-541-2198 E-MAIL: Click here to email the contact person., pricer.shari@epamail.epa.gov. The U.S. Environmental Protection Agency's National Exposure Research Laboratory located at Research Triangle Park, NC (NERL/RTP) is issuing a "Request for Assistance" (RFA). The objective of this RFA is to encourage innovative research approaches to reducing uncertainty in the area of mathematical modeling of human exposure. Specifically, this RFA solicits proposals for cooperative research to represent total human exposure and source-to-dose relationships through development of mathematical models and databases which operate in a multimedia environment capable of representing these relationships at spatial scales ranging from geographic regions to personal and residential microenvironments. Applications that respond to this RFA may be submitted by not-for-profit research institutions such as universities, federal research laboratories, and nonprofit research institutes. The research objectives for this RFA support the long-term research priorities of EPA's Office of Research and Development (ORD). ORD has identified research to strengthen the scientific foundation for human health risk assessment as one of its six high priority areas. The funding mechanism that will be used to support research under this RFA is the cooperative assistance agreement. The selection of this research mechanism reflects ORD's decision to sustain joint scientific collaboration in the design, conduct, and interpretation of research supported under this agreement through the expertise of principal investigators from both the recipient organization and ORD's National Exposure Research Laboratory (NERL). ORD may elect to fund one, or more than one, cooperative research agreement from applications that respond to this solicitation. The anticipated duration of the cooperative research agreement(s) is five years. The anticipated funding rate for the cooperative agreement(s) will be approximately $500,000 per year for total (direct plus indirect) costs of $ 2.5 million. In response to electronic or written requests, NERL/RTP will mail out a solicitation package on or after March 16, 1998 which will describe the requirements of the RFA. Electronic requests should be e-mailed to "pricer.shari@ epamail.epa.gov". Written requests may be mailed to the U.S. Environmental Protection Agency, National Exposure Research Laboratory, MD-78A, 79 T. W. Alexander Drive, Research Triangle Park, NC 27711, Attn: Shari Pricer. Responses to the RFA are due at NERL/RTP not later than the close of business (5:00 p.m.), Eastern Daylight Time, May 15, 1998. (0061)

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