NASA/George C. Marshall Space Flight Center, Procurement Office, Marshall Space Flight Center, AL 35812

A -- BRINGING GREATLY ENHANCED LABORATORY-BASED PROTEIN CRYSTALLOGRAPHY TO THE U.S. BIOTECHNOLOGY COMMUNITY DUE 101797 POC Marty B. Hanson, Contract Specialist, Phone (205) 544-0989, Fax (205) 544-9354, Email marty.hanson@msfc.nasa.gov -- David A. Iosco, Contracting Officer, Phone (205) 544-0387, Fax (205) 544-9354, Email david.iosco@msfc.nasa.gov WEB: Click here for the latest information about this notice, http://procurement.nasa.gov/EPS/MSFC/date.html#W-8-FA-32917. E-MAIL: Marty B. Hanson, marty.hanson@msfc.nasa.gov. The contractor will be required to participate in an ongoing collaborative project with NASA, the National Institute of Health, the University of Albany, and X-Ray Optical Systems, Inc. to develop and use novel x-ray technology for enhancing laboratory-based protein crystallography. A strategic part of the project is to develop the capability to predictably and controllably manufacture monolithic polycapillary X-ray optics. The contractor will define the x-ray system requirements for use in protein crystallography research; evaluate the performance of the system and carry out selected crystal structure measurements; explore options and limitations with respect to sample mounting and cooling, goniometer configuration, detector resolution and collimation; develop software and procedures for system use; and conduct theoretical and experimental studies on the feasibility of monochromatic convergent beam methods and application to protein crystallographic data acquisition. This procurement is being conducted under the NASA MidRange Pilot Test Program approved by the Office of Federal Procurement Policy. NASA/MSFC intends to purchase the items from New Century Pharmaceuticals, Inc., 895 Martin Road, Huntsville, AL 35812 since this company is the only known source with the capabilities and experience required for this project. See Numbered Note 26. Interested firms have 15 days from publication on the NAIS (or Commerce Business Daily (CBD) if over $500K) to submit their qualifications/capabilities. Such qualifications/capabilities will be used solely for the purpose of determining whether or not to conduct this procurement on a competitive basis. Responses received after 15 days without the required information will be considered nonresponsive to the synopsis and will not be considered. A determination by the Government not to compete this proposed contract, on a full and open competitive basis, based upon responses to this notice, is solely within the discretion of the Government. All responsible sources may submit an offer which shall be considered by the agency. Any referenced numbered notes can be viewed at the following URL: http://genesis.gsfc.nasa.gov/nnotes.htm. (0273)

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