U.S. ARMY MEDICAL RESEARCH, ACQUISITION ACTIVITY, ATTN MCMR-AAA-B BLDG 820 FORT DETRICK, FREDERICK MD 21702-5014

A -- POTENTIAL SOURCES SOUGHT SOL CBD&&&-9512-0002 POC PATRICIA M. MCALLISTER, CONTRACTING OFFICER (301) 619-7360 (Site Code DAMD17) The U.S. Army Medical Research and Materiel Command is currently developing reactive topical skin protectants (rTSPs) to provide protection to soldiers who may be exposed to chemical warfare agents (CWAs) on the battlefield. Proposals addressing the identification and synthesis of reactive (stoichiometric and/or catalytic) materials capable of neutralizing one, or preferably more than one CWA, e.g., the vesicating agent sulfur mustard (HD), the ''G'' nerve agents soman (GD), sarin (GB), tabun (GA), and the nerve agent VX, when incorporated into a base cream containing perfluorinated alkylpolyether oil and polytetrafluoroethylene particulates are of interest. The final formulation of reactive material and base oil will be applied to human skin and must prevent the penetration of CWA to the skin and avert the toxic effects of skin contact with CWAs. The base cream formulation has already been demonstrated to provide a physical barrier against CWAs. The reactive materials to be incorporated must enhance the barrier effect by chemically neutralizing the CWAs before the barrier is penetrated. The final formulation should have reasonable cost, be safe and nonirritating, chemically stable, demonstrate rapid kinetics, and have acceptable user characteristics. Successful proposals must contain a viable concept for development of reactive materials and demonstrate a logical sequence of steps to identify, synthesize, and formulate these reactive materials into a final product of the type described above. Efficacy testing will be conducted by the U.S. Army Medical Research Institute of Chemical Defense (USAMRICD). Contact the Contracting Officer outlined in number 11 above for instructions regarding submission of preproposals under the Broad Agency Announcement. (0341)

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