National Cancer Institute, Research Contracts Branch, PSCS Executive Plaza South, Room 638, Bethesda, MD 20892-7228

65 -- LCQ BENCHTOP MSN SYSTEM MASS SPECTROMETER SOL N02-CB-56239-83 POC Sarah Payne, Contract Specialist or Janet Mattson, Contracting Office r, 301/402-4509. Under the authority of 41 U.S.C. 253 (c) (1), FAR 6.302-1, The National Cancer Institute (NCI) intents to negotiate with Finnigan Corp., 355 River Oaks Parkway, San Jose, CA 95134 for a LCQ Benchtop MSn System Mass Spectrometer. The system shall consist of a quadruple ion trap mass spectrometer capable of detecting ions in the range of 20 amu to 2000 amu. The mass spectrometer will be interfaced with a variable flow (1ul - 2000ul per minute) atmospheric pressure ionization (API) source to allow for the ionization of mixtures via a variable flow HPLC device. The mass spectrometer shall be of a bench-top design and dimension of 23'' x 30'' x 30'' because of limited laboratory floor space. The system must include a proven API source with an ESI probe that has fully automated tuning and optimization (no manual adjustments required), sample disolvation by a heated metal capillary for efficient ion transfer, snap-in capillary/skimmer design for easy maintenance, automated source gas shut off for unattended operation, and liquid sheath flow for 100% aqueous mobile phases. The option for atmospheric pressure chemical ionization (APCI) shall be available as well as an HPCE interface. The mass spectrometer mass analyzer shall be based on a quadruple ion trap design, and shall have an internally regulated helium flow design for stable operation. Ions shall be introduced into the mass analyzer by dual octapole ion optics for efficient operation. The mass spectrometer shall utilize full scan operation, selected ion monitoring (SIM) operation, full scan MS/MS, selected reaction monitoring (SRM) with MSn, and a narrow range high resolution mode to allow for resolved isotopic envelopes of multiply-charged ions of up to four charges and automatically determine the correct molecular weight. This notice of intent is not a request for competitive proposals, however, if an interested party believes they can meet the above specifications, they may submit a statement of capabilities. Information furnished shall include enough material, in sufficient detail to perform a proper evaluation of their ability to perform. Closing date is 45 days after publication of this notice. See note #22. (0181)

Loren Data Corp. http://www.ld.com (SYN# 0576 19950703\65-0001.SOL)