U.S. ARMY MED. RESEARCH ACQUISITION ACT, MCMR-RMA (PGI-3), FORT DETRICK BLDG. 820, FREDERICK MD 21702-5014

A -- CLINICAL RESEARCH AND OTHER STUDIES PERSIAN GULF WAR ILLNESSES SOL DAMD17-95-#-0010 MCMR-RMA (PGI-3) DUE 082395 POC CRAIG D. LEBO, 301-619-2036 (i) DAMD17-95-#-0010; (ii) Award will be made in accordance with the guidelines of the R&D Streamlined Contracting procedure outlined in DFARS 235.700O; (iii) Supplemental package; (iv) availability of supplemental; (v) All mandatory terms, clauses and provision in DFARS 235.7006 and the following optional items are incorporated by reference: (B.6, C.3, E.3, F.1, G.1,G.4, I.43, I.46 to I.51, I.53, I.55, I.56, I.63, I.64, I.70, I.75, I.78, I.79, I.86, I.88, I.89,I.94, I.97, I.98, I.104, I.106. I.107, I.124, I.125, I.127 to I.129, I.160, I.164; (vi) Clauses and provisions are those in effect through FAC 90-24, dated 15 DEC 94 and DAC 91-6, dated 27 May 1994; (vii) The standard evaluation factors at Section M apply to this RDSS with the following exceptions: Factor M.1 is deleted in its entirety and factor M.2 (ii) A(1) is supplemented - ''As part of the technical approach an assessment of whether the proposal clearly addresses a relevant and significant military problem that can be solved by research and development studies.'' Factor M.2 (ii) A(2) is supplemented -''Applicants must have demonstrated expertise in epidemiology, neurobiology, toxicology or pharmacology; and must have no financial relationship with any company that manufactures a product that may be addressed in the study.''; (viii) The resultant contract will normally require the timely delivery of several reports during the research effort, specifically a quarterly financial report, a Mid-Term Scientific Report and a Final Report. Additionally, publication of study results in peer reviewed scientific journals is imperative; (ix) A cost reimbursement contract is anticipated. However, the government reserves the right to award grants or cooperative agreements as a result of this solicitation. (x) The period of performance should not exceed three years. Specific products and delivery dates will be negotiated with each successful grantee; (xi) No preproposal conference is planned; (xii) No small business or other set-asides apply to this action. (xiii) Technical and cost proposals are due no later than 2:00 pm Eastern Daylight Time 23 August 1995, to Building 820, Fort Detrick, Frederick, Maryland 21702-5014 M/F DAMD17-95-#-0010; (xiv) Proposals shall be submitted in an original and 19 copies. (xv) No proposal page limit is mandated except that indicated in Section L.24 (see also FAR 52.215-7); Multiple awards are anticipated; Point of Contact Craig D. Lebo, U.S. Army Medical Research Acquisition Activity, Building 820, Fort Detrick, Frederick, Maryland 21702- 5014 (telephone 301-619-2036, fax, 301-619-2937), email, craig_lebo@ftdetrck-ccmail.army.mil; (xviii) There are no applicable CBD notes; (xx) Statement of work: The U.S. Army Medical Research and Materiel Command (USAMRMC), on behalf of the Departments of Defense, Veterans Affairs, and Health and Human Services Cooperative Research Program, is supporting clinical studies and other research on the health consequences of military service or employment in the Southwest Asia theater of operations during the Persian Gulf War. The USAMRMC is seeking proposals for clinical studies and other research on the cause(s), mode(s) of transmission(s), and appropriate treatment(s) of Persian Gulf War illnesses. Proposals should be in the basic sciences, preclinical, or clinical arena and focus on individuals who served in Southwest Asia in the military, as DoD or contractor employees, or spouses and children of deployed personnel, where appropriate, during the Persian Gulf War. Proposals are sought which specifically address stress related psychiatric conditions including post-traumatic stress disorder and somatoform disorders; improved prevention methods, better diagnostic tools for infectious diseases (including field screening tests); and enhanced treatment procedures for viral, bacterial, fungal, rickettsial, and parasitic diseases (e.g. Leishmania tropica) common to Southwest Asia; as well as chronic fatigue syndrome. Proposals are also requested to assess lead exposure in the theater of operations and its possible effects, possible reproductive toxins, mycotoxins, petrochemical toxicity, pesticide poisoning, untoward reactions to anthrax vaccines and Botulinum toxoids, ingestion/inhalation of silica and sand, depleted uranium, and the effects of possible exposure to other chemical hazards and agents.(0142)

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