National Library of Medicine, Office of Acquisitions Management, 8600 Rockville Pike, Building 38A, Room B1N17, Bethesda, Maryland 20894

D -- BIOTECHNOLOGY INFORMATION SOFTWARE SUPPORT SOL NLM 95-108/RMC DUE 051995 POC Robin M. Cummings, Contract Specialist (301) 496-6546. The National Center for Biotechnology Information (NCBI), a division of the National Library of Medicine (NLM), requires the services of a contractor who employs senior-level systems analysts and programmers with advanced skills in scientific and database software development. The contractor shall provide software systems design and programming assistance to the intramural research and development efforts of the NCBI staff in implementing major new systems for the solution of scientific database design, searching, and analysis problems caused by the rapid growth of molecular biology information, specifically molecular sequence data. The contractor shall perform tasks in designated application areas using various hardware and software systems provided by the Government. The contractor shall be required to use any of the hardware systems listed below, or other systems, as specified in task orders: Servers - Multiprocessor Sun SPARCcenters and SPARCservers, and Silicon Graphics Challenge; Workstations - Sun SPARCstations, Silicon Graphics, other Unix-based workstations, PC-compatibles, and Macintosh. The contractor shall be required to have expertise in any of the software systems listed below, or other systems, as specified in task orders: Networking - Client-server applications, TCP/IP protocols, NFS, distributed databases; Operating Systems - UNIX, Windows, Macintosh OS; Languages - C, C++, SQL, ASN.1; Windowing Systems - X Windows, Motif, Microsoft Windows, Macintosh; Databases - Sybase SQL Server. The contractor shall be required to perform tasks in designated application areas such as those listed below, or other areas, as specified by task order: scientific database management including data collection, entry, verification, maintenance, and dissemination; standards-based graphical user interface front-end software to database applications; distributed software applications using local area or wide area networks, particulary database-related applications and/or applications employing distributed windowing systems; database design, incorporating data representations that are optimal for search, analysis, transmission, and storage of factual and bibliographic data, particularly biological data; methods and algorithms for improving the efficiency of information retrieval; software algorithms and other database query methods for translating queries into appropriate retrievals from multiple related factual databases; and methods of applying advanced hardware and software systems (e.g., parallel and multiprocessing architectures, multithreaded operating systems) to problems of data retrieval and sequence analysis. A cost-reimbursement type contract using a task ordering mechanism with a term of five (5) years is contemplated. Release of the Request for Proposals (RFP) is contingent upon receipt of a Delegation of Procurement Authority. All responsible sources may submit a proposal which will be considered by the National Library of Medicine. Copies of Request for Proposals NLM 95-108/RMC will be available on or about fifteen (15) days from publication of this announcement. Copies may be obtained by writing to the National Library of Medicine, Office of Acquisitions Management, 8600 Rockville Pike, Building 38A, Room B1N17, Bethesda, Maryland 20894, Attention: Robin M. Cummings, Contract Specialist. Telephone/FAX requests will not be accepted. See Numbered Note(s): 1. (0124)

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