National Cancer Institute, Research Contracts Branch, Cancer Etiology Contracts Section, EPS/620, 6120 EXECUTIVE BLVD MSC 7224

A -- SUPPORT SERVICES FOR EPIDEMIOLOGIC STUDIES SOL N01-CP-15672 POC Barbara A. Shadrick, Contracting Officer, 301/496-8611. The National Cancer Institute (NCI), Division of Cancer Etiology (DCE), Epidemiology & Biostatistics Program (EBP), Environmental Epidemiology Branch (EEB) intends to negotiate with Westat, Incorporated, for an 11-month extension of Contract Number N01- CP-15672 to allow for the continuation and completion of a study entitled ''Nasopharyngeal Carcinoma (NPC) Family Study'' currently being conducted under subcontract with the National Taiwan University. This project began in February 1991 and is expected to be completed by January 26, 1997. The intent is to follow high-risk families with the goal of increasing our understanding of the genetic factors involved in NPC pathogenesis and the impact of viral and environmental factors on these genetic factors. The on-going collaboration between NCI and the National Taiwan University has resulted in the identification of a large registry of families at high risk of developing NPC. Given the unique size and nature of this registry, NCI, in collaboration with the National Institute of Dental Research (NIDR) will conduct the extension of this project through NCI's contract with Westat, Incorporated. AUTHORITY: 41 U.S.C. 253(c)(1), as set forth in FAR 6.302-1(a)(2)(ii) and HHSAR 306.302-1(a)(2)(ii). Inherent duplication of cost to the government and unacceptable delays in establishing a relationship with the patient population make competition unfeasible for this study which provides for longer follow-up and data analysis. If, however, there are any responsible sources who feel that there are extenuations which would enable them to perform the requirement, they must respond within 45 days from the date of publication of this notice. No collect calls will be accepted. See Note(s): 22. (0060)

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