Loren Data Corp.

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COMMERCE BUSINESS DAILY ISSUE OF FEBRUARY 22,1995 PSA#1288

National Institute of Environmental Health Sciences, Contracts and Procurement Management Branch, OM, 79 T.W. Alexander Drive, P.O. Box 12874, 4401 Building, Research Commons, Research Triangle Park, NC 27709

A -- REPRODUCTIVE OUTCOMES AND ENVIRONMENTAL POLLUTION SOL NIH-ES-95-28 POC Contact Velvet M. Torain, Contract Specialist, 919/541-0400; Phillip D. Jones, Contracting Officer, 919/541-0426 The National Institute of Environmental Health Sciences intends to negotiate a contract with University of Illinois, School of Public Health, Chicago, Illinois, 1) to obtain and validate the reproductive database of the Children of Ukraine study for the 3000 participants who contributed biological samples (this consists of 3 questionnaires from the parents and medical records on the pregnancy) 2) to obtain existing environmental measurements in the study sites and evaluate their validity; 3) to describe placental pathology in the study cohort and to identify any associations with reproductive outcome or with adverse reproductive effects with levels of environmental pollutants to include metals, organo-chlorine pesticides, PAHs, and radiation. Authority: 41 USC 253(c)(1), as set forth in FAR 6.302-1. The proposed project is an extension of a pilot study conducted for the NIEHS by the University of Illinois Ukrainian Environmental Health Project and the Ukrainian Institute of Pediatrics, Obstetrics and Gynecology. The project capitalizes on a group of multinational studies initiated in 1985 by the World Health Organization studies known as the European Longitudinal Study of Pregnancy and Childhood (ELSPAC). The University of Illinois has responsibility for overseeing the Ukrainian portion of ELSPAC studies and is the only organization that can provide data associated with the samples collected during the pilot study. Because the ELSPAC studies are currently in progress, the Government will be able to obtain these data much sooner than if a new study were initiated by the NIEHS. The costs associated with initiating a new study in an effort to obtain the same type of data would be unreasonable considering that the data already exist, and the lack of convertible currency and contract law in Ukraine make contracting directly with the Ukrainian Institute unfeasible for the U.S. Government. See Note 22 (0048)

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