National Cancer Institute, Research Contracts Branch, Cancer Etiology Contracts Section, EPS/620, 6120 EXECUTIVE BLVD MSC 7224, BETHESDA MD 20892-7224

A -- RESOURCE FOR PROCUREMENT OF HUMAN TISSUES FROM DONORS WITH AN EPIDEMIOLOGICAL PROFILE SOL NCI-CP-62602-13 DUE 031395 POC Sharon A. Miller, Contracting Officer, (301) 496-8611. The Division of Cancer Etiology, National Cancer Institute, has a requirement for a resource for procurement of human tissues from donors with an epidemiologic profile. This will include (1) providing human broncus, lung and colon specimens following surgeries, organ transplants, and immediate autopsies; (2) obtaining appropriate human subject and informed consent approvals; (3) performing pathological analysis (morphological, cytochemical and immunocytochemical characteristics) of collected tisues from the fresh, unfrozen, normal, premalignant and malignant tissues to define conditions of the specimens at ''time 0'' of collection; (4) delivery of tissues to NIH within 2 hours of availability; (5) obtaining participation from smoking and nonsmoking male and female adults; (6) collecting viable specimens of blood components; (7) delivering donor questionnaires to NIH. All responsible sources are encouraged to submit an offer and will be considered by the NCI. No collect calls will be accepted. (0010)

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