SOLICITATION NOTICE
R -- PAXGENE Ribonucleic acid extraction, quality?control?and aliquoting services
- Notice Date
- 6/10/2026 7:33:05 AM
- Notice Type
- Presolicitation
- NAICS
- 541714
— Research and Development in Biotechnology (except Nanobiotechnology)
- Contracting Office
- NATIONAL INSTITUTES OF HEALTH OLAO BETHESDA MD 20892 USA
- ZIP Code
- 20892
- Solicitation Number
- 75N98026Q00583
- Response Due
- 6/20/2026 6:00:00 AM
- Archive Date
- 06/21/2026
- Point of Contact
- John Burton
- E-Mail Address
-
burtonjo@mail.nih.gov
(burtonjo@mail.nih.gov)
- Small Business Set-Aside
- NONE No Set aside used
- Description
- Requirements 3.0 OBJECTIVE The objective of this requirement is to procure PAXgene ribonucleic acid extraction, quantitation, normalization, Agilent quality control, and aliquoting services for samples collected from 50 clinical participants in support of ongoing NIDDK clinical protocol research and downstream transcriptomic analysis. These services are necessary to support research involving gene expression profiling, molecular characterization of biospecimens, identification of disease mechanisms, and evaluation of potential therapeutic targets through transcriptomic analysis. 4.0 CONTRACTOR REQUIREMENTS The contractor shall provide PAXgene ribonucleic acid extraction and aliquoting services for 122 PAXgene tube units collected from 50 clinical participants. Services shall include ribonucleic acid extraction, quantitation, normalization, Agilent quality control testing, aliquoting, frozen storage, and shipment on dry ice. The contractor shall perform high-quality ribonucleic acid extraction from PAXgene tubes using validated protocols and established laboratory procedures. The contractor shall perform ribonucleic acid quantitation and normalization to ensure consistent sample concentrations suitable for downstream transcriptomic analysis. The contractor shall perform deoxyribonuclease (DNase) treatment to remove genomic deoxyribonucleic acid contaminants and ensure clean ribonucleic acid preparations. The contractor shall perform ribonucleic acid integrity and quality assessments using Agilent instrumentation to verify sample suitability for downstream transcriptomic analysis. The contractor shall aliquot up to twenty-one (21) aliquots per sample and provide secure frozen storage conditions to prevent sample degradation prior to shipment. The contractor shall maintain complete documentation and traceability records, including logging of processing steps and sample status throughout all stages of handling and processing. Quality Control Upon receipt, all specimens shall meet the contractor�s established quality control acceptance criteria for processing. The contractor shall inspect all specimens upon receipt and immediately notify NIDDK of any compromised, damaged, or nonconforming specimens requiring replacement. The contractor shall verify specimen integrity upon delivery through visual inspection and temperature monitoring procedures. Repository Management The contractor shall provide certificates of analysis and donor documentation for each specimen, as applicable. The contractor shall provide shipping documentation and chain-of-custody records to NIDDK upon delivery. The contractor shall ensure specimens are maintained and stored under appropriate frozen conditions throughout handling, storage, and shipment activities. The contractor shall provide order status updates and shipment tracking information to designated NIDDK personnel throughout the period of performance.
- Web Link
-
SAM.gov Permalink
(https://sam.gov/workspace/contract/opp/f91d48e1d50d46f0a448bb7ecca64bd8/view)
- Place of Performance
- Address: MD 20892, USA
- Zip Code: 20892
- Country: USA
- Zip Code: 20892
- Record
- SN07847031-F 20260612/260610230126 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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