Loren Data's SAM Daily™

SAMDAILY.US - ISSUE OF APRIL 01, 2026 SAM #8892
SOLICITATION NOTICE

66 -- MALDI-TOF Biotyper Sirius

Notice Date

3/30/2026 1:06:53 PM
 

Notice Type

Combined Synopsis/Solicitation
 

NAICS

334516 — Analytical Laboratory Instrument Manufacturing
 

Contracting Office

FDA OFFICE OF ACQ GRANT SVCS Rockville MD 20852 USA
 

ZIP Code

20852
 

Solicitation Number

75F40126R00030
 

Response Due

3/10/2026 9:00:00 AM
 

Archive Date

03/25/2026
 

Point of Contact

Erika Crawford, Phone: 3017960298
 

E-Mail Address

erika.crawford@fda.hhs.gov
(erika.crawford@fda.hhs.gov)
 

Small Business Set-Aside

NONE No Set aside used
 

Description

The select agent laboratory at Moffett participates in the Laboratory Response Network (LRN) for detecting botulinum neurotoxins (BoNTs). Traditional mouse bioassays, though the gold standard, are costly, slow, and raise ethical concerns. Previously, DIG-ELISA kits were used for high-throughput screening to reduce animal use, but these kits are being phased out in favor of the Endopep-MS (Endopeptidase�Mass Spectrometry) assay. Developed over 10 years by CDC�s Biological Mass Spectrometry Laboratory, the Endopep-MS assay detects BoNT activity on peptide substrates that mimic the toxin�s natural targets. This method eliminates animal testing and allows high-throughput analysis, supporting rapid response in large-scale events. The FDA requires one (1) Bruker MALDI-TOF Biotyper Sirius one GP system to replace an obsolete instrument. The system must support Endopep-MS assays for detection, differentiation, and characterization of Clostridium botulinum neurotoxins, maintaining operational capability critical to mission readiness and public health protection.
 

Web Link

SAM.gov Permalink
(https://sam.gov/workspace/contract/opp/57fa8276a2354fddb818b0385e04a6ba/view)
 

Place of Performance

Address: Summit Argo, IL 60501, USA

Zip Code: 60501

Country: USA
 

Record

SN07762090-F 20260401/260330230050 (samdaily.us)
 

Source

SAM.gov Link to This Notice
(may not be valid after Archive Date)

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