SOLICITATION NOTICE
A -- Generative Optogenetics (GO)
- Notice Date
- 12/19/2025 2:07:57 PM
- Notice Type
- Solicitation
- NAICS
- 541714
— Research and Development in Biotechnology (except Nanobiotechnology)
- Contracting Office
- DEF ADVANCED RESEARCH PROJECTS AGCY ARLINGTON VA 222032114 USA
- ZIP Code
- 222032114
- Solicitation Number
- DARPA-PS-26-10
- Response Due
- 2/26/2026 4:00:00 PM
- Archive Date
- 03/28/2026
- Point of Contact
- Dr. Matthew J. Pava, Program Manager
- E-Mail Address
-
GO@darpa.mil
(GO@darpa.mil)
- Description
- The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative concepts to design a protein complex that can be expressed in vivo (i.e., in a living cell) and responds to optical signals to synthesize a corresponding DNA or RNA sequence. This technology should enable massless transfer of genetic information to cells expressing the protein complex via a template-free mechanism that incorporates nucleotide bases in response to specific optical signals (e.g., different wavelengths of light). The GO program is focused on two main Research Objectives (ROs): (1) achieving the core capability of synthesizing DNA/RNA directly in living cells using optical signals, and (2) developing error mitigation methods that ensure high-fidelity nucleic acid synthesis. The acquisition process for GO will proceed through a two-stage process, starting with (1) written abstracts which will inform invitations to brief (2) an Oral Proposal Package (OPP) at DARPA.
- Web Link
-
SAM.gov Permalink
(https://sam.gov/workspace/contract/opp/330a7d73f8e44c2ca588697555e48829/view)
- Record
- SN07671193-F 20251221/251219230031 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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