SOURCES SOUGHT
B -- PANDHA-25-P-0000_003354 DNA Aptamer-based Therapeutic Development
- Notice Date
- 3/25/2025 5:03:25 AM
- Notice Type
- Sources Sought
- NAICS
- 541714
— Research and Development in Biotechnology (except Nanobiotechnology)
- Contracting Office
- ARMY MED RES ACQ ACTIVITY FORT DETRICK MD 21702 USA
- ZIP Code
- 21702
- Solicitation Number
- PANDHA-25-P-0000_003354
- Response Due
- 4/1/2025 7:00:00 AM
- Archive Date
- 04/16/2025
- Point of Contact
- Linda Hinson, Sharew Hailu
- E-Mail Address
-
linda.t.hinson.civ@health.mil, sharew.hailu.civ@health.mil
(linda.t.hinson.civ@health.mil, sharew.hailu.civ@health.mil)
- Description
- The objective of this contract is to conduct a two-year study on conjugated aptamers as antimicrobial agents to produce DNA aptamers conjugated with C1q- and Fc-domain proteins to create a biologic therapeutic with immunomodulatory antimicrobial activity against bacterial pathogens for wound infection. This shall include producing DNA aptamers that bind to the bacterial pathogen Pseudomonas aeruginosa; conjugating DNA aptamers to recombinant C1q protein and to recombinant IgG Fc domain protein to produce C1q- and Fc-conjugated DNA aptamers; validating that C1q- and Fc-conjugated DNA aptamers bind to Pseudomonas aeruginosa; and delivering C1q- and Fc-conjugated DNA aptamers to WRAIR, AFRIMS for testing, located in Bangkok, Thailand.
- Web Link
-
SAM.gov Permalink
(https://sam.gov/opp/b2e95305f51b4315b6cd4b31b88f871d/view)
- Place of Performance
- Address: BANGKOK, TH-10, THA
- Country: THA
- Country: THA
- Record
- SN07385521-F 20250327/250325230050 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
| FSG Index | This Issue's Index | Today's SAM Daily Index Page |