SPECIAL NOTICE
A -- Specialized Genetic Sequencing Services (VA Research Study)
- Notice Date
- 3/19/2025 12:50:57 PM
- Notice Type
- Special Notice
- NAICS
- 541715
— Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- Contracting Office
- RPO EAST (36C24E) PITTSBURGH PA 15212 USA
- ZIP Code
- 15212
- Solicitation Number
- 36C24E25Q0034
- Response Due
- 3/26/2025 8:59:00 AM
- Archive Date
- 05/25/2025
- Point of Contact
- Ms. Millicent Covert, Contracting Officer, Phone: (Calls shall not be taken)
- E-Mail Address
-
millicent.covert@va.gov
(millicent.covert@va.gov)
- Awardee
- null
- Description
- Regional Procurement Office (RPO) - East intends to negotiate on a sole source basis, pursuant to FAR 6.302-1, with Novogene Corporation, Inc., for specialized genetic sequencing services for the Research Department at the Minneapolis VA Health Care System. These services are required for the VA-funded research study Impact of Obesity on Brain Immune Response and Cognition . The objective of the study is to determine key features that differentiate the spatial configuration and expression profile of mouse brain from either WT or Alzheimer s Disease expressing (AD) mice with confounding factors such as high-fat diet or environmental toxin exposure. We may identify new targets for AD treatment by identifying two new mechanisms of disease progression: 1) Enhanced neuroinflammation due to exacerbation of inflammatory factors due to high-fat diet or environmental toxin exposure in the AD background. 2) Identification of new disease mechanisms may improve the care of Veterans with AD, high-fat diet, and/or environmental toxin exposure thereby decreasing costs for the Veterans Affairs Health Care System. Highly experienced in providing data from large-scale sequencing projects, Novogene has been involved in previous studies directly related to the current study. To ensure consistent support, data readability and compatibility, continuation of Novogene s services is crucial to the study s successful outcome. Novogene (contractor/contractor laboratory) shall: Process, sequence, and quantify the RNA from samples on a massive scale with high-accuracy, dependability, and reproducibility. Perform RNA library preparation, sequence the RNA, and prepare a data output including sequence identity and quantity for all samples. Provide start-to-finish advanced genetic sequencing and quantitation services tailored to the analysis of single-cells. Provide accurate and reproducible quantitative results for a variety of tissue types and sequencing modalities. The VA laboratory anticipates sending 4 to 20 samples per year depending on experimental outcomes. This is a notice of intent and is not a request for competitive quotes; however, any responsible source that believes it is qualified to meet this unique need may submit a capability statement to the contracting office no later than Wednesday, March 26, 2025, 11:59 AM EST. Interest/capability statements may be sent to Millicent Covert, Contracting Officer, at millicent.covert@va.gov. No telephone responses will be accepted. A determination not to compete the proposed requirement based upon the responses to this notice is solely within the discretion of the Government.
- Web Link
-
SAM.gov Permalink
(https://sam.gov/opp/20d169f4cc624be384d88c8efa19111d/view)
- Record
- SN07377095-F 20250321/250319230045 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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