SOURCES SOUGHT
70 -- MBF Bioscience Software Upgrade and Support Services
- Notice Date
- 6/13/2024 11:23:21 AM
- Notice Type
- Sources Sought
- NAICS
- 513210
—
- Contracting Office
- NATIONAL INSTITUTES OF HEALTH NIA ROCKVILLE MD 20852 USA
- ZIP Code
- 20852
- Solicitation Number
- 75N95024Q00356
- Response Due
- 6/27/2024 1:00:00 PM
- Archive Date
- 07/12/2024
- Point of Contact
- ERIC MCKAY, Phone: 3014802406
- E-Mail Address
-
eric.mckay@nih.gov
(eric.mckay@nih.gov)
- Description
- This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement. This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement, to determine the method of acquisition, and availability of domestic sources manufactured in the United States in sufficient and reasonably available commercial quantities and of a satisfactory quality.� It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract.� Responses will not be considered as proposals or quotes.� No award will be made as a result of this notice.� The Government will NOT be responsible for any costs incurred by the respondents to this notice.� This notice is strictly for research and information purposes only. Small businesses are encouraged to respond. For equipment/supply requirements, responses must include the place of manufacturing (i.e. address if supply/equipment is a domestic end product and include country of manufacture). For equipment/supply requirements, small businesses must also address the size status of the manufacturer under the applicable NAICS code (i.e. address Non-Manufacturer Rule). Background: Neurocognitive Aging Section (NAS) needs to renew and upgrade software subscriptions and support services for MBF Bioscience products that they use in conjunction with their microscope systems in order to continue ongoing NAS experiments. Purpose and Objectives: NAS staff conducts numerous experiments that include morphometric analysis of brain tissue visualized on one of their microscope systems. To do this, NAS has equipped their microscope/imaging systems with MBF Bioscience software that allows for analysis such as cell counting, cell size assessment, neuron tracing, and tract tracing. In order for these systems to continue to work properly NAS needs to renew the software subscription and support services for this fiscal year. Project requirements: The following software is required: Software for System #1 (Leica DMRB Microscope System) Stereo Investigator - Microscope Edition: 1-year Software Upgrade and Support Services. Provides software upgrades and remote online and telephone technical support. Software for System #2 (Leica DM4000 Microscope System) Neurolucida - Microscope Edition: 1-year Software Upgrade and Support Services. Provides software upgrades and remote online and telephone technical support. Stereo Investigator - Microscope Edition: 1-year Software Upgrade and Support Services. Provides software upgrades and remote online and telephone technical support. Software for System #3 (Stand-Alone System) Neurolucida - Desktop: 1-year Software Upgrade and Support Services. Provides software upgrades and remote online and telephone technical support. Software for System #4 (3D Core Solution Suite) Term License Renewals Annual Subscription for Facilities Solution: 3D Suite Includes a suite of the following MBF Bioscience software with a mobile license: -Neurolucida 360 Studio -Vesselucida 360 Studio -Stereo Investigator - Desktop -Stereo Investigator - Cleared Tissue -MicroFile+ -Mobile License Upgrade Annual Subscription for Neurolucida 360 Studio - Automatic neuron tracing and quantitative analysis software, with tools to automatically detect reconstruct and edit somas, dendrites, axons, spines, varicosities, and puncta in 3D. Salient Characteristics: - Full 3D environment for image visualization, rotation and zooming - Handles large, high-resolution brightfield & fluorescence (wide field, confocal, two photon & light sheet) images - Subvolume mode for instant navigation and integrated subvolume tracing in very large images - Batch mode for unattended automatic tracing of multiple image files - Image montaging for automated 3D alignment of multiple3D image stacks - Clean Up feature for automatic auditing of tracing Annual Subscription for Vesselucida� 360- Software for automaic reconstruction and analysis of vessels and microvasculature. Salient Characteristics: - Full 3D environment for image visualization, rotation and zooming - Smart manual mode for targeted manual vessel tracing in 3D - User-guided mode for quick and easy semi-automatic vessel tracing in 3D - Automatic mode for the fastest fully automatic vessel tracing in 3D - Batch mode for unattended automatic vesel tracing of multiple image files - Handles big, high-resolution brightfield & fluorescence (widefield, confocal, two-photon & lightsheet) images - Includes Software Upgrade and Support Services - Requires Windows 10, 64 bit, PC (not included). Annual Subscription for Vesselucida Explorer -Windows 10 version: Salient Characteristics: Generate data reports - From individual vessels to entire vascular structure VEX-10-12c - From defined diameters of segments - On continuous vessel segments Anastamoses Analyses - Define loops, number of nodes, avg. diameter - Data reports on anastamoses in vasculature - Navigate through loops without having to run an analysis Batch Analysis - Run multiple analyses on multiple data files simultaneously - Save files directly into Microsoft Excel Annual Subscription for Stereo Investigator - Cleared Tissue Edition: Analysis software for performing unbiased stereology on whole or partial specimens that have been cleared using methods such as CLARITY, 3DISCO, FluoClearBABB, etc. that have been imaged using lightsheet, confocal scanning, or 2-photon microscopes. Includes the capability to directly read most lightsheet, confocal, and 2-photon microscope 3D image stacks. Also includes Software Upgrade and Support Services Annual Subscription for Stereo Investigator - Desktop Edition version (no control of motorized microscope, stage or camera). For unbiased stereology, image analysis, and 2D anatomical mapping. Includes the capability to read in most confocal, brightfield and fluorescent 3D image stacks. Requires Windows 10, 64 bit, PC (not included). Indudes 12 months of software license, software upgrades and technical support. Mobile License Upgrade. Allows installation of software on multiple PCs, only one of which can be used at any given time. Annual Subscription for Neurolnfo Studio: Automatically delineate and identify mouse brain regions in experimental specimens based on the digital Allen Mouse Brain Atlas. Includes BrainMaker for creating full-resolution 3D images from serial sections. Also includes Software Upgrade and Support Services. Salient Characteristics: - Registers serial section images of any orientation to the Allen Mouse Brain Atlas - Delineates anatomies in the experimental anatomic space - Automatic cell detection and reporting on cell number within selected anatomies - Corrects for distortion due to histological processing - Combines all image measurements to anatomies in the Allen Mouse Brain Atlas for cross cohort, or experiment comparisons. BrainMaker includes functionality to: - Combine data from multiple whole-slide images or virtual slides - Specify serial section order across slides - Automatic alignment of serial sections with optional manual intervention - Automatic correction of upside-down and flipped sections - Save registered sections as 3D image volumes at selectable output resolutions - 3D Visualization of aligned image volumes - Read all major whole-slide image file formats All aligned image volumes are compatible with Neurolucida and Stereo Investigator for quantitative analysis, and can be served by Biolucida for analysis or collaboration Annual Subscription for Neurolucida Explorer - Windows 10 version: Salient Characteristics: - Enhanced 3D environment to zoom, pan & rotate - Structural, anatomical, spatial, and orientation analyses of neurons: - Branch Angle & Structure - Dendrogram & Vertex - Closed Surface & Proximity - Tangential Distribution - 3D Wedge, Convex Hull, Sholl - Layer Length & Wedge - Polar Histogram & Fan-In Diagram - Structural, anatomical, and anastomoses analyses of vessels (exclusive to the ""Neurolucida 360 Ultra"" package) - Puncta colocalization and spatial analyses - Marker & Region analysis - Batch analysis for running multiple data files simultaneously - Automatic export to Microsoft Excel Software for System #5 (Stand-Alone System) Stereo Investigator - Desktop: 1-year Software Upgrade and Support Services. Provides software upgrades and remote online and telephone technical support. Software for System #8 (Vesalius System) Microlucida: 1-year Software Upgrade and Support Services. Provides software upgrades and remote online and telephone technical support. Software for System #10 (Stand-Alone System) Term License Renewals Annual Subscription for Neurolucida 360 Studio - Automatic neuron tracing and analysis, with tools to reconstruct and edit somas, dendrites, axons, spines, varicosities, and synapses in 3D. Salient Characteristics: - Full 3D environment for image visualization, rotation and z0oming - Smart manual mode for targeted manual neuron tracing in 3D - User-guided mode for quick and easy semi-automatic neuron tracing in 3D - Automatic mode for the fastest fully automatic neuron tracing in 3D - Clean Up feature for automatic auditing of tracing: exclusive to Studio package - Batch mode for unattended automatic neuron tracing of multiple image files - Integrated subvolume tool for dynamic tracing of very large images; exclusive to Studio package - Automatic dendritic spine detection, modeling, classification; exclusive to Studio package - Automatic detection and modeling of puncta in 3D with specialized machine learning capability; exclusive to Studio package - Automatic varicosity detection; exclusive to Studio package - Image montaging for automated 3D alignment of multiple 3D image stacks - Handles big, high-resolution brightfield & fluorescence (wide field, confocal, two-photon & light sheet) images - Includes Software Upgrade and Support Services - Requires Windows 10, 64 bit, PC (not included). Annual Subscription for Neurolucida Explorer - Windows 10 version: Salient Characteristics: - Enhanced 3D environment to zoom, pan & rotate - Structural Analysis: Branch Angle & Structure Dendrogram & Vertex -Anatomical Analysis: Closed Surface & Proximity Tangential Distribution -Spatial Analysis: 3D Wedge, Convex Hull, Sholl Layer Length & Wedge -Orientation Analysis: Polar Histogram & Fan-In Diagram Colocalization analysis Marker & Region analysis Automatic export to Excel Advanced 3D movies Anticipated period of performance: The anticipated period of performance consists of a base period and three 12-month option periods as follows: Base Period: 9/24/2024 � 9/23/2025 Option Period 1: 9/24/2025 � 9/23/2026 Option Period 2: 9/24/2026 � 9/23/2027 Option Period 3: 9/24/2027 � 9/23/2028. Other important considerations: In case domestic sources are available and capable of fulfilling the Government�s need, and a future solicitation is published, the Government will use evaluation preferences in accordance with FAR 25. Capability statement /information sought. Companies that believe they possess the capabilities to provide the required products should submit documentation of their ability to meet each of the project requirements to the Contracting Officer. The capability statement must specifically address each of the project requirements separately.� Additionally, the capability statement should include 1) any contractor GSA Schedule contracts and/or other government-wide acquisition contracts (GWACs) by which all of the requirements may be met, if applicable, and 2) any other information considered relevant to this program. Capability statements must also include the Company Name, Unique Entity ID from SAM.gov, Physical Address, and Point of Contact Information. The response must include the respondents� technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses. Interested companies are required to identify their type of business, applicable North American Industry Classification System (NAICS) Code, and size standards in accordance with the Small Business Administration. The government requests that no proprietary or confidential business data be submitted in a response to this notice. However, responses that indicate the information therein is proprietary will be properly safeguarded for Government use only. Capability statements must include the name and telephone number of a point of contact having authority and knowledge to discuss responses with Government representatives. Capability statements in response to this market survey that do not provide sufficient information for evaluation will be considered non-responsive. When submitting this information, please reference the solicitation notice number. One (1) copy of the response is required and must be in Microsoft Word or Adobe PDF format using 11-point or 12-point font, 8-1/2� x 11� paper size, with 1� top, bottom, left and right margins, and with single or double spacing. The information submitted must be in and outline format that addresses each of the elements of the project requirement and in the capability statement /information sought paragraphs stated herein.� A cover page and an executive summary may be included but is not required. The response is limited to ten (10) page limit.� The 10-page limit does not include the cover page, executive summary, or references, if requested. All responses to this notice must be submitted electronically to the Contract Specialist and Contracting Officer.� Facsimile responses are NOT accepted. The response must be submitted to Eric McKay, Contracting Officer, at email address eric.mckay@nih.gov. The response must be received on or before June 27, 2024, 4:00 pm, Eastern Time. Disclaimer and Important Notes:� This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization�s qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a presolicitation synopsis and solicitation may be published in www.sam.gov. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).
- Web Link
-
SAM.gov Permalink
(https://sam.gov/opp/96bb8bb769c14a74904ff15d246db876/view)
- Place of Performance
- Address: Baltimore, MD 21224, USA
- Zip Code: 21224
- Country: USA
- Zip Code: 21224
- Record
- SN07097403-F 20240615/240613230128 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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