Loren Data's SAM Daily™

SAMDAILY.US - ISSUE OF SEPTEMBER 19, 2023 SAM #7966
SOLICITATION NOTICE

66 -- Seahorse XF HS Mini Analyzer

Notice Date

9/17/2023 6:51:07 PM
 

Notice Type

Combined Synopsis/Solicitation
 

NAICS

334516 — Analytical Laboratory Instrument Manufacturing
 

Contracting Office

RPO EAST (36C24E) PITTSBURGH PA 15212 USA
 

ZIP Code

15212
 

Solicitation Number

36C24E23Q0094
 

Response Due

9/19/2023 8:00:00 AM
 

Archive Date

10/19/2023
 

Point of Contact

Shannon Hukriede, Contract Specialist, Phone: (will not take calls)
 

E-Mail Address

shannon.hukriede@va.gov
(shannon.hukriede@va.gov)
 

Awardee

null
 

Description

Page 6 of 6 This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotes are being requested and a written solicitation will not be issued. This is a Request for Quote (RFQ) and the solicitation number is 36C24E23Q0094. The government anticipates awarding a firm-fixed price contract resulting from this combined synopsis/solicitation. This solicitation is issued Full and Open Competition for Brand Name Only. It is the responsibility of the contractor to be familiar with the applicable clauses and provisions. The clauses may be accessed in full text at www.acquisition.gov. STATEMENT OF NEED (SON) CONTRACT DESCRIPTION AND REQUIREMENTS The Atlanta VA Medical Center requires an Agilent Seahorse XF HS Mini Analyzer to replace an existing, older Agilent Seahorse Analyzer that has reached the end of its life expectancy for use in ongoing research studies. The Agilent Seahorse XF HS Mini Analyzer is required to maintain research data continuity and integrity for the multiple projects requiring mitochondrial and bioenergetic phenotyping of cultured cells. A firm-fixed price contract will be awarded for the purchase of brand name equipment in accordance with all terms, conditions, provisions, specifications and schedule of this solicitation herein. Quotes shall contain the Offeror s best terms for cost/price and technical capabilities of the required Agilent Seahorse XF HS Mini Analyzer. The government reserves the right to award without discussions. 1.1 PRICING The Offeror shall submit price quotes for the required brand name or equal equipment to the specifications listed in Section 1.2 below. Please enclose the established price list and description of capabilities and product specifications for the required equipment. The Offeror shall submit a separate price sheet for equal items to include Manufacturer Name, Stock/Part #, Unit of Issue and Price. Items offered that are brand name or equal shall identify items as being on GSA schedule and reference the contract number for each item. Note: The Offeror should include a description of any support services or warranty information in the technical quote. 1.2 REQUIRED PRODUCTS & SPECIFICATIONS ITEM INFORMATION ITEM NUMBER DESCRIPTION OF SUPPLIES/SERVICES QUANTITY UNIT UNIT PRICE AMOUNT 0001 1.00 EA _____________ __________ **BRAND NAME ONLY** Seahorse XF HS Mini Analyzer measures oxygen consumption rate and proton efflux rate of live cells in an 8-well format. Includes embedded Win 10 controller and miniplates. With the following configuration: Ship-to Country : USA Installation (44K) Introduction (44L) LOCAL STOCK NUMBER: S7852A 0002 1.00 EA _____________ __________ Shipping/Handling, Freight Charges GRAND TOTAL __________ 1.3 Product Capabilities & Salient Characteristics or equal This request is for **BRAND NAME ONLY** equipment required to support multiple investigators throughout the Atlanta VAMC Research Department requiring mitochondrial and bioenergetic phenotyping of cultured cells. The Vendor will supply a mini analyzer that requires the following specifications and salient characteristics: Agilent Seahorse XF HS Mini Analyzer complete with specified attachments, components, installation, and support. This equipment is needed to replace an existing Agilent Seahorse that has reached the end of its life expectancy for use in ongoing research studies. The Agilent Seahorse XF HS Mini Analyzer is required to maintain research data continuity and integrity and will be compatible with the same reagents and consumables, which are specific to each machine. It must have: Initial installation and set-up of the machine onsite Initial onsite training for the analyzer and associated software One-year warranty included Agilent Seahorse XF Technology Simultaneously measures oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) of living cells. Using these measurements, glycolytic Proton Efflux Rate (PER) is easily calculated as an accurate measurement of glycolysis rates in real time. Quantitative ATP production rates can also be calculated in real time using well-validated proprietary algorithms. Performs a non-invasive measurement that does not require the addition of dyes, labels, or reporters. Measurements may be repeated to measure kinetic responses over several hours without causing unhealthy hypoxic or acidic conditions. Measures adherent cells without requiring trypsinization; suspension cells can be measured by attachment to the well bottom. Typically requires only 1x104 to 1x106 cells per well in the 24-well system; 5x103 to 5x105 per well in the 96-well and 8-well platform. Cells/microplate remain viable following an Agilent Seahorse XF assay and may be used for another assay. Measurement technology is covered by US patent # 7,276,351, EU Patent 1664740, and other issued and pending patents throughout the world. For Research Use Only. Not for use in diagnostic procedures. Agilent Seahorse XFe and XF HS Mini Analyzers Instrument creates transient microchamber, makes optical measurements, and performs compound injections. Up to four test compounds may be added automatically to each well during the assay. Measurements may be performed before and after each compound is added. Temperature controlled measurement chamber is maintained at 37°C ± 0.5°C; alternative temperatures supported. XFe analyzers are also supported to for analysis in a hypoxic chamber. OCR and ECAR data are simultaneously calculated and displayed in real time. OCR and ECAR enable for calculations of glycolytic PER and ATP production rates. Rates are automatically calculated and reported every 5-8 minutes. Data are reported in calibrated rates of pmol/min or mpH/min. No cleaning is required. All the parts that are in contact with the cells, media, or compounds are disposable. Data analysis is done with Seahorse Analytics, a cloud-based platform designed expressly for analyzing and interpreting Seahorse XF assay results. Wave Desktop software provides an alternative way to view assay results and export into MS® Excel, Graphpad Prism, or Seahorse assay-specific reports. Excitation and Emission Light Emitting Diodes (LEDs) are used as the monochromatic excitation source. LEDs are operated at very low excitation energy densities to prevent detectable levels of photobleaching. The usable life of the LED sources is >10,000 hours. Narrow band pass filters control spectral adherence. Enclosure The precision-molded enclosures on Agilent Seahorse XFe and XFp Analyzers have specialty coatings and gaskets to shield the electronics and sample from ambient light, as well as block radiated and emitted electromagnetic interference. Agilent Seahorse XF Assay Kits and Reagents Convenient, easy-to-use Seahorse XF test kits and Seahorse XF reagents simplify the study of cellular metabolism by providing pre-calibrated, pre-tested reagents for routine measurements of metabolic phenotype, mitochondrial respiration, glycolysis, and fatty acid oxidation, and ATP production rates. Standardized reagents, kits, and protocols are designed and validated for use with Agilent Seahorse XF analyzers. Convenient, quality-controlled kits provide standardized metabolic measurements in an easy-to-use format. Kits are simple, cost-effective and support reproducible results. Agilent Seahorse XF Sensor Cartridges and Microplates Only Agilent Seahorse XF sensor cartridges are compatible with Agilent Seahorse XF instruments and must be used during an Agilent Seahorse XF assay. Agilent Seahorse XF Cell Culture Microplates and Miniplates have a unique geometry required for the XF measurements and are tissue culture treated for optimal cell growth. Optical sensors do not consume oxygen during the measurement and are not in contact with the cells. Optical sensors are not affected by compound or intracellular dye fluorescence. Oxygen sensor peak absorption = 530 nm (green). Oxygen peak emission = 650 nm (red). pH sensor peak absorption = 470 nm (blue). pH sensor peak emission = 530 nm (green). Each sensor cartridge is auto-calibrated at the beginning of the run. Sample preparation steps are automation compatible with an Agilent Bravo automated liquid handler or similar device. Data Quality Because Agilent Seahorse XF assays are non-invasive, multiple measurements may be made to monitor samples over several hours. Measurement-to-measurement within the same well demonstrates a coefficient of variation of 5%, approximately equivalent to the instruments background noise. Total variability between wells from all sources (instrument background plus biological variability due to cells) for the average trained user is <20%. The product capabilities and salient characteristics identified above by a brand name or equal"" description are intended to be descriptive, not restrictive, and to indicate the quality and characteristics of the product that will be satisfactory. Quotes offering ""equal"" products (including products of the brand name manufacturer other than the one described by the brand name) will be considered if such product is clearly identified in the quote and is determined by the VA to meet fully the salient characteristics on above products. If offering an equivalent product, the brand name of the equivalent product shall be clearly identified in the quote. Unless visibly identified as an equivalent product, offered items shall be considered as the brand name product referenced in this announcement. The evaluation of quotes and the determination as to the equality of the products shall be the responsibility of the Government and shall be based on information provided by the Offeror. The Government is not responsible for locating or securing any information not provided in the quotation by the Offeror. To ensure that sufficient information is available, the Offeror must furnish, as a part of the quote, all descriptive material necessary for the purchasing activity to determine whether the products meet the salient characteristics of this requirement. Vendors proposing to modify a product to make it conform to the requirements of this announcement shall include a clear description of the proposed modification and clearly mark any descriptive material to show the proposed modification. Offers that do not have descriptive material will not be considered for award. 1.4 General Information Type of Contract: Firm Fixed Price Place of Delivery Address: Atlanta VA Medical Center 1670 Clairmont Rd. NE Decatur, GA 30033 Attn: Dr. Samantha Yeligar, Room 12C-177 404-321-6111 x207163 Postal Code: 30033 Country: UNITED STATES Instructions to the Offeror Basis for award resulting from this RFQ will made to the Best Value Offer that provides a complete package pursuant to the preparation requirements set forth in 52.212-1. FAR 52.212-2 (Evaluation - Commercial Items) will be incorporated in full text into the RFQ and will be evaluated on the following factors. Evaluations will be in accordance with FAR 13 Simplified Procedures. Evaluation Factors for Award: Factor 1 - Technical Capabilities All offerors must meet or exceed all requirements and salient features as listed in the Statement of Need. Factor 2 - Past Performance - Past Performance will be based on the most current PPIPRS Report. Factor 3 - Price The following FAR provision and clauses apply to this solicitation and are incorporated by reference. The solicitation document, incorporated provision and clauses are those in effect through the Federal Acquisition Circular (FAC) 2023-05, Effective September 7, 2023. It is the responsibility of the contractor to be familiar with the applicable clauses and provisions. The clauses may be accessed in full text at www.acquistion.gov. This contract incorporates one or more clauses by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. FAR 52.212-1 Instructions to Offerors Commercial FAR 52.212-2 Evaluation- Commercial Items FAR 52.212-3 Offeror Representations and Certifications FAR 52.212-4 Contract Terms and Conditions FAR 52.212-5 Contract Terms and Conditions Required To Implement Statutes Or Executive Orders Commercial Item FAR 52.219-6 Notice of Total Small Business Set-Aside (Nov 2011) FAR 52.219-8 Utilization of Small Business Concerns (Oct 2014) FAR 52.233-3 Protest After Award (Aug 1996) FAR 52.211-6 Brand Name or Equal FAR 52.233-2 Service of Protest Quotes shall be submitted via email to shannon.hukriede@va.gov and Offerors must reference Solicitation 36C24E23Q0094 in the subject line of the email. No telephone request for information will be considered. Incomplete packages will be considered nonresponsive. All offers must be received by the closing date Tuesday, September 19, 2023, NLT 3:00 PM EDT.
 

Web Link

SAM.gov Permalink
(https://sam.gov/opp/623b937f547d49d2a51dd3c8eb047737/view)
 

Place of Performance

Address: Atlanta VA Medical Center 1670 Clairmont Rd. NE, Decatur 30033

Zip Code: 30033
 

Record

SN06834269-F 20230919/230917230047 (samdaily.us)
 

Source

SAM.gov Link to This Notice
(may not be valid after Archive Date)

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