SOLICITATION NOTICE
D -- Health Brain Network Supplement to Track Homeostatic Regulatory Domains in Youth in the General Community
- Notice Date
- 7/21/2022 7:42:20 AM
- Notice Type
- Presolicitation
- NAICS
- 541511
— Custom Computer Programming Services
- Contracting Office
- NATIONAL INSTITUTES OF HEALTH NIDA Bethesda MD 20892 USA
- ZIP Code
- 20892
- Solicitation Number
- NIMH22005168NOI
- Response Due
- 7/31/2022 2:00:00 PM
- Point of Contact
- Christopher Michael Halstead, Phone: 301-451-1517
- E-Mail Address
-
christopher.halstead@nih.gov
(christopher.halstead@nih.gov)
- Description
- This is a notice of intent, not a request for a quotation. A solicitation document will not be issued, and quotations will not be requested. The general purpose of this acquisition is to implement the concepts and procedures from studies in the IRP to translate the findings to youth mental health. The major goals of the IRP collaboration would be to advance the primary research goals of our research groups on mood disorders in order to identify links between mood disorders and their underlying dimensional manifestations with objective measures of motor activity and sleep, and mood reactivity and instability and broad outcomes including suicidal behavior, social and educational impairment and onset of emotional and behavior disorders. Data from multiple domains including symptoms, impairment, neuroimaging, reactivity, psychophysiology, motor activity and sleep, cognitive function, and genetics that were collected in the first wave will be used to identify profiles of risk and outcome. The specific goal of this proposed award is to extend this research to include families of study participants because of the compelling evidence for the importance of the familial context of mental and physical health in youth. We plan to recruit the parents and siblings of the existing sample and complete recruitment of the 100 youth in the study. This pilot study of youth for the NIMH Rhythms and Blues Study involves intensive clinical characterization and mobile assessments over a one-year period. This effort will complete the pilot study that tests acceptability and uptake of follow up in order to build a larger effort with external funding for the Child Mind Institute (CMI) and Nathan Kline Institute faculty and collaborators to follow up the full sample of youth. Data provided from this work can be added to the international collaborative effort on rhythms of motor activity, sleep and mood now being led by the IRP through the motor activity research consortium for health (mMARCH) and to the neuroimaging and cognitive data networks in youth in which several IRP investigators are currently involved. Analyses and findings will be greatly facilitated by the growing NIMH IRP computational sophistication on analyses of these multi-level repeated measures data in several labs at the NIMH IRP. The three subaims of this supplement are to: (1) collect information on the parents and siblings of the sample in order to gain insight into the familial correlates of the key study domains; (2) to expand the measures of daily rhythms to include tracking of light exposure, and measures of ambulatory sleep, heart rate variability, and salivary and blood biomarkers; and https://www.danielledick.com/ and (3) to develop summary dashboards for the parents and participants and automated summaries of the diagnostic interview for the clinical reviewer through writing of computer programs that automate output extracted from salient measures from the clinical diagnostic interview (e.g. DASH) and mobile assessments. Through existing contractual agreements, the Matter Lab at the Child Mind Institute has already developed some of the applications and computerized the clinical tools for the collaborative studies between the NIMH IRP and Healthy Brain Network (Prior contract numbers: 75N95B19P00070, 75N95B19P00175 and 75N95020P00378). Mindlogger�s data collection platform is now actively being used by research studies funded by the NIMH and the Child Mind Institute�s Healthy Brain Network. The Matter Lab is uniquely positioned to assume the next phase of this work by expanding the MindLogger platform to administer semi-structured interviews and provide summary dashboards and reports. All tools built in MindLogger will be accessible for use in studies at both the Child Mind Institute and the NIMH intramural program, as well as any other interested researchers. The Child Mind Institute Healthy Brain Network (CMI-HBN) is to recruit up to 500 existing participants to be followed based on their available profiles of motor activity, sleep, mood instability and social sensitivity to intensively characterize these domains using mobile assessments over a one-year period, with frequent online tracking of mental health and behavior. The CMI-HBN is uniquely qualified to fulfill this role as the baseline data needed to identify and recruit participants has already been collected, and the staff have extensive experience administering the necessary protocols. Additionally, the Child Mind Institute is to develop the infrastructure (data schema, managing user permissions) to fully support the implementation of semi-structured interviews which include dashboards and reports to collect data from, and share results with, research participants for the NIMH IRP. The project will result primarily in data collection that will result in joint publications and coordination of international activities on activity and mood disorders and symptoms. As such, no other vendor can provide the Government with the required service and maintenance renewal. This acquisition is being conducted using policies unique to the Federal Acquisition Regulation (FAR) Part 13 � Simplified Acquisition Procedures, Subpart 13.106-1(b)(1), For purchases not exceeding the simplified acquisition threshold (SAT), contracting officers may solicit from one source if the contracting officer determines that the circumstance of the contract action deem only one source reasonably available. Contracts awarded using FAR Part 13-Simplified Acquisition Procedures are exempt from the requirements of FAR Part 6-Competition Requirements. Interested parties may identify their interest and capabilities in response to this posting. The determination by the Government not to compete the proposed requirement based upon responses to this notice is solely within the discretion of the Government. Comments to this announcement, referencing this posting number, may be submitted to the CC, Office of Purchasing and Contracts, prior to the closing date specified in this announcement, electronically to the attention of Christopher Halstead, Contract Specialist, Christopher.Halstead@nih.gov by the due date and time marked in this notice.
- Web Link
-
SAM.gov Permalink
(https://sam.gov/opp/36545cf8b1364ac88b120f6c767a9a88/view)
- Place of Performance
- Address: Bethesda, MD 20892, USA
- Zip Code: 20892
- Country: USA
- Zip Code: 20892
- Record
- SN06396911-F 20220723/220721230116 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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