SOURCES SOUGHT
D -- D-Glucose-2,5-13C2 99% Non-hazardous compound, 20 Grams
- Notice Date
- 7/19/2022 8:15:42 AM
- Notice Type
- Sources Sought
- NAICS
- 541714
— Research and Development in Biotechnology (except Nanobiotechnology)
- Contracting Office
- NATIONAL INSTITUTES OF HEALTH NIDA Bethesda MD 20892 USA
- ZIP Code
- 20892
- Solicitation Number
- NIH_NIMH_22004619SS
- Response Due
- 8/4/2022 2:00:00 PM
- Archive Date
- 08/05/2022
- Point of Contact
- Tiffany Stone, Phone: 301.480.7158, Christine Frate, Phone: 301.443.3846
- E-Mail Address
-
tiffany.stone@nih.gov, christine.frate@nih.gov
(tiffany.stone@nih.gov, christine.frate@nih.gov)
- Description
- NIH's National Institute of Mental Health's Magnetic Resonance Spectroscopy Unit is conducting studies of Neurotransmission and Neurometabolism in Rats. We have� been� conducting� several� in� vivo� carbon-13 (13C) spectroscopy� projects� with� infusion� of� 13C� labeled �chemicals.�� Because natural abundance of 13C is only 1%, the signal is too weak to be detected. Therefore, we need to use chemicals with enriched 13C to increase 13C signal intensity. In an ongoing project, D-GLUCOSE-2,5-13C2 will be used to study brain metabolism. Each in vivo rodent study will use between 10-50mg of D-GLUCOSE-2,5-13C2 depending on the specific study. With these 13C labelled chemicals, we will be able to detect brain metabolism and to accurately measure the concentrations of several important metabolites. The 13C MR spectroscopy methods developed in this group is and will be applied to many other research groups in NIMH and NIH for various neural science studies. Without this chemical, the institute will lose a powerful method of neural science research. Delivery is needed within 4 months of purchase order.
- Web Link
-
SAM.gov Permalink
(https://sam.gov/opp/ea7b90b2d72146a088a26f60c69a4a68/view)
- Place of Performance
- Address: Bethesda, MD 20814, USA
- Zip Code: 20814
- Country: USA
- Zip Code: 20814
- Record
- SN06394534-F 20220721/220719230059 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
| FSG Index | This Issue's Index | Today's SAM Daily Index Page |