SPECIAL NOTICE
66 -- Intent to sole source - Live Cell Analysis System (VA-21-00079110)
- Notice Date
- 5/16/2022 9:59:29 AM
- Notice Type
- Special Notice
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- RPO EAST (36C24E) PITTSBURGH PA 15212 USA
- ZIP Code
- 15212
- Solicitation Number
- 36C24E22Q0153
- Archive Date
- 08/23/2022
- Point of Contact
- Lynn M Portman, lynn.portman@va.gov, Phone: (412) 822-3442
- E-Mail Address
-
lynn.portman@va.gov
(lynn.portman@va.gov)
- Awardee
- null
- Description
- Page 1 of 1 The Department of Veterans Affairs, Oklahoma City VA, intends to negotiate on a sole source basis, pursuant to FAR 6.302-1, with Satorius for the IncuCyte S3 HD/2CLR Live Cell Analysis system. The unique patented technology allows investigators in determining the cell morphology, cell health, movement and function of cell models, and in studying complex cell-cell interactions from hours to days over time by live cell imaging and analysis data in real-time. The automation of the IncyCyte S3 system is an required by the investigators as it allows acquiring and analyzing phase-contrast and fluorescence images of the cells without disturbing the cells or removing the cells from the incubator. The IncuCyte suite of applications will be used in areas of oncology, immune-oncology, immunology, neuroscience, aging, diabetes, drug discovery, and nanomedicine. Using the system, investigating various aspects of cell functions and behavior and response to treatment is feasible that could lead to developing novel therapeutics, and new areas of research. The equipment s unique design has a microscope with fixed sample stage that offers uninterrupted incubation of a range of cell types - from proliferating tumor cells to non-adherent immune cells to sensitive primary cells. The system is versatile and has interchangeable trays to accommodate tissue culture flasks, dishes, or multi-well plates. The IncuCyte S3 system allows the visualization (by phase-contrast and fluorescence) and monitoring of cell health and proliferation (eg: cell counting, apoptosis, tumor spheroid, cell-cycle, etc.); cell function (eg: phagocytosis, NETosis, angiogenesis, immune cell killing, neuronal activity, antibody internalization, etc.); cell movement and morphology (eg: scratch wound assay, cell migration and invasion, neurite outgrowth, immune cell activation, etc.); binding of biological and non-biological materials (drug, nanoparticle, cell-particle interaction, antibody binding to cell, etc.); measurement of receptor-mediated binding and entry into cells (nanoparticles, quantum-dots, virus, bacteria, metals, antibodies, etc.); and intracellular localization and trafficking (siRNA, plasmid DNA, nanoparticles, virus, bacteria, spores, etc.). All of these biological and functional activities can be captured in real-time using the time-lapse system and the data presented visually in image format and numerically in graphical format. The IncuCyte S3 system also includes the requisite software system for generating customer-specific protocols. Since the protocols can be automated, once the experiment in particular the time-lapse imaging starts, the user can walk-away from the instrument while the samples are being processed, which frees the user to perform other experiments or analyses. This is a notice of intent and is not a request for competitive quotes; however, any responsible source who can provide an equivalent product with these features described above may submit a capability statement to the contracting office no later than May 23th, 4:30PM, EST. Interest/capability statements may be sent to Lynn Portman at lynn.portman@va.gov. No telephone responses will be accepted. A determination not to compete the proposed requirement based upon the responses to this notice is solely within the discretion of the Government.
- Web Link
-
SAM.gov Permalink
(https://sam.gov/opp/7da4647230184b3daf9a8c503df130b0/view)
- Record
- SN06327855-F 20220518/220516230059 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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