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SAMDAILY.US - ISSUE OF MARCH 16, 2022 SAM #7411
SOLICITATION NOTICE

66 -- Notice of Intent to Sole Source - ACES2 proteins utilizingcryo-EM methodologies

Notice Date
3/14/2022 7:40:21 AM
 
Notice Type
Combined Synopsis/Solicitation
 
NAICS
541715 — Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
 
Contracting Office
CDC OFFICE OF ACQUISITION SERVICES ATLANTA GA 30333 USA
 
ZIP Code
30333
 
Solicitation Number
64675
 
Response Due
3/17/2022 6:00:00 AM
 
Archive Date
04/01/2022
 
Point of Contact
Kourtney Marshall, Phone: 4044984280
 
E-Mail Address
qrz9@cdc.gov
(qrz9@cdc.gov)
 
Description
The Centers for Disease Control and Prevention intends to award sole source firm fixed price purchase order to Emory University for ACES2 protein utilizingcryo-EM methodologies. Expression and purification of sixteen (16) SARS-CoV-2 or ACE2 proteins, with a minimum yield of 1mg per protein, the determination of ten (10) structures of Spike-ACE2 complexes utilizing cryo-EM methodologies, and eighteen (18) negative stain EM images of inactivated SARS-CoV-2 virions.�Entities further from the CDC would lose time in transition (shipping one day in each direction), when plasmids and proteins can be exchanged directly on the same day they are created due to the close proximity of Emory. Couple this with anticipated turn around times (TAT) of 15-days for protein expression and purification, and 4-6 weeks for solving protein structurers, and the Liang lab provides significantly faster service.�Several other vendors were contacted, None of them had the�capacity to even start on a new project in under 5 months, and all projected significantly longer TAT�s at each step, and much higher costs.
 
Web Link
SAM.gov Permalink
(https://sam.gov/opp/8bc2475a7127481081d315c6b3a3095d/view)
 
Record
SN06266372-F 20220316/220314230100 (samdaily.us)
 
Source
SAM.gov Link to This Notice
(may not be valid after Archive Date)

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