SPECIAL NOTICE
A -- Notice of Intent to Sole Source - Six (6) Joint Warfighter Medical Research Program Projects
- Notice Date
- 1/27/2022 1:57:31 PM
- Notice Type
- Special Notice
- NAICS
- 541715
— Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- Contracting Office
- W4PZ USA MED RSCH ACQUIS ACT FORT DETRICK MD 21702-5014 USA
- ZIP Code
- 21702-5014
- Solicitation Number
- W81XWH-FY21-Notice-of-Intent-to-Sole-Source-JWMRP
- Response Due
- 2/11/2022 9:00:00 AM
- Point of Contact
- Jennifer E. Hayden
- E-Mail Address
-
jennifer.e.hayden.civ@mail.mil
(jennifer.e.hayden.civ@mail.mil)
- Description
- Notice of Intent to Award Sole Source FY2021 Joint Warfighter Medical Research Program (JWMRP) The United States Army Medical Research Acquisitions Activity (USAMRAA), on behalf of the U.S. Army Medical Research and Development Command (USAMRDC), is issuing this Notice of Intent to Award Sole Source. This is not a request for proposals. This notice does not represent a commitment by the government to pay for costs incurred from the preparation and/or submission of data in response to this notice. This is a notice of the intent to award six (6) sole source contracts to six (6) contractors that met the criteria of the FY2021 Joint Warfighter Medical Research Program (JWMRP) in accordance with FAR 6.302-1(a)(2), Only One Responsible Source and No Other Supplies or Services Will Satisfy Agency Requirements. Information regarding the intended sole source awards is listed below. University of Nebraska Medical Center Description: The proposed research addresses the needs of the Radiation Health Effects Research Program (RHERP) within the Joint Warfighter Medical Research Program (JWMRP). RHERP focuses on developing medical countermeasures for acute ionizing radiation injury to prevent or treat the effects of acute radiation syndrome (ARS). Specifically, this proposal will address the post-exposure mitigation of radiation injury by further evaluating the efficacy of 5-Androstene-3?-17?-diol (5-AED), a promising, undeveloped agent for preventing ARS. Several preclinical studies demonstrated that 5-AED either protected mice from whole body irradiation or mitigated the effects of radiation in nonhuman primates. A previous Phase I trial demonstrated that 5-AED was well-tolerated and safe in humans. Unfortunately, the further development of 5-AED was hindered by the mismanagement and the ultimate bankruptcy and failure of a start-up company. Thus, 5-AED has great promise as a potent radiomitigator that warrants further investigation. Wake Forest University Health Sciences Description: The objective of this project is to develop purpose-built pumps and blood pressure sensors that work in tandem with the Precision Automated Critical Care Management (PACC-MAN) software algorithms to deliver care, focusing on a simple yet robust design that is compact, energy-efficient, rugged, and reliable. There is a need to implement software upgrades to facilitate clinical end user experience, as opposed to the current lab-grade versions. It must be ensured that this platform delivers on its promise, by comparing its performance to standard �best practices'' using manual care delivered by an experienced clinician. The focus of this submission is to meet these objectives. The insights and technological developments gained from this work will bring the PACC-MAN platform closer to a clinically viable entity, paving the way for rapid transition to human trials. U.S. Army Institute of Surgical Research (USAISR) Description: This proposal will test a new enzymatic debrider, SN514 has shown a faster activity profile in animal studies than Collagenase Santyl Ointment (CSO). The animal studies performed suggest SN514 provides safe and tolerable non-surgical debriding for wounds. The formulation of SN514 provides a room temperature stable product that is easily applied to the wound. SN514 would provide a novel non-surgical debridement product that could be used for prolonged field care of injured personnel, during mass casualty events, and for small rural areas with limited access to high level medical facilities. CytoSorbents, Inc. Description: The objective of this proposal is to combine the CytoSorbents blood group antibody (BGA) filtration device with freeze-dried plasma (FDP) preparation for the ultimate deployment-ready blood product. Specifically, this will entail scale up the production of blood group A and B ligands that are used in the BGA Adsorber and ultimately integrate this with the freeze-drying process. This proposal addresses the needs across the spectrum of emergency care including advanced hospital-based care and field resuscitation. Additionally, the antibody depleted universal FDP shipped from the continental US can be administered at any stage in theater or used in civilian or Veteran�s Administration hospitals to resuscitate hemorrhaging trauma or surgical patients. Design Interactive, Inc. Description: AUGMED� Mobile is an Extended Reality (XR) training system that uses virtual, augmented, and mixed reality technologies to provide contextualized and embodied medical Tactical Combat Casualty Care (TCCC) training. This anywhere, anytime hands-on Joint Training Solution for military personnel is designed to be refresher and classroom training that fundamentally transforms and exponentially improves the approach to TCCC training. The primary goal for this proposed effort is to build upon previous development efforts to extend AUGMED� Mobile into a fully operational training system. This will be achieved by configuring the system to work across all mobile devices, conducting user experience evaluations and enhancements, achieving Risk Management Framework (RMF) Compliance through Cybersecurity System Hardening, performing a training effectiveness evaluation of the system and achieving Authority to Operate (ATO). Vcom3D, Inc. Description: The objective of the proposed Network-enabled Casualty Combat Care (NETC3) Scale-up is to advance this technology from an early prototype to a system for integrating combat casualty care into the tactical training of squads before they are deployed to fight. By using emerging gaming and simulation technology, NETC3 will provide more cost-effective training with greater flexibility than training that is dependent upon expensive medical manikins, thereby reducing taxpayer burden. The NETC3 Scale-up will also incorporate a virtual patient into the AR display � one that can graphically represent various traumatic injuries. This will provide an effective form of stress inoculation training that will prepare soldiers for the life-threatening conditions they will face on the battlefield. Congress appropriated $40M for the Joint Warfighter Medical Research Program in the �Consolidated Appropriations Act, 2021�, Public Law 116-260. The U.S. House of Representatives Report of the Committee on Appropriations together with Minority Views states in House Report 116-453 that the funds �shall be used to augment and accelerate high priority Department of Defense (DoD) and Service medical requirements and to continue prior year initiatives that are close to achieving their objectives and yielding a benefit to military medicine.� These funds shall not be used for new projects nor for basic research, and it shall be awarded at the discretion of the Secretary of Defense following a review of medical research and development gaps as well as unfinanced medical requirements of the Services� (page 327). For this reason, it was determined that the cited statutory authority permitting other than full and open competition is supported and required. This Bill essentially limits the competition to contractors that have existing research projects that have received funding from the Department of Defense (contracts or assistance agreements) and have a military relevance. The Bill also states that funds shall be awarded at the discretion of the Secretary of Defense following a review of medical research and development gaps. The strategy in executing the JWMRP was to find highly valued research efforts on research grants or contracts that could meet critical service requirements and that were not being continued through other appropriations.� This notice is provided solely as information to the marketplace. CONTACT INFORMATION:� Questions may be submitted to Ms. Jennifer Hayden at jennifer.e.hayden.civ@mail.mil no later than 12:00PM Eastern on 11 February 2022.� �
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- Record
- SN06226142-F 20220129/220127230109 (samdaily.us)
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