SOURCES SOUGHT
66 -- Purchase of a Functional Ultrasound Capable of measuring blood flow changes with high spatial-temporal resolution.
- Notice Date
- 6/24/2021 2:15:29 PM
- Notice Type
- Sources Sought
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- NATIONAL INSTITUTES OF HEALTH NIDA Bethesda MD 20892 USA
- ZIP Code
- 20892
- Solicitation Number
- NINDS21007702
- Response Due
- 7/8/2021 9:00:00 AM
- Archive Date
- 07/09/2021
- Point of Contact
- Kristina Jenkins, Phone: 3014027464
- E-Mail Address
-
kristina.jenkins@nih.gov
(kristina.jenkins@nih.gov)
- Description
- This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of qualified businesses to perform a potential requirement. This notice is issued to help determine the availability of qualified small businesses technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. Statement of Need and Purpose: The NIH Mouse Imaging Facility (MIF) has received a request from a number of investigators for an ultrasound that is capable of doing functional ultrasound (US).� This is an exciting new techniques that enables one to measure changes in regional blood flow at the temporal and spatial resolution of US.� To perform this it takes a specialized type of US called power doppler US.� It is expected that the requested equipment will be used to study regional brain changes in blood flow in rodents as well changes in blood flow in tumors and skeletal muscle.� The MIF has over 100 active projects and it is expected that many of these projects will benefit from functional US. Background: The NIH Mouse Imaging Facility (MIF) is a shared, intramural resource for preclinical animal imaging studies. The MIF provides the NIH intramural research community access to modern radiological imaging equipment optimized for rodents and other laboratory animals for noninvasive imaging studies. The MIF provides intellectual, technical and material support for NIH investigators. MIF imaging resources include magnetic resonance imaging (MRI), micro-computed tomography (Micro-CT), high frequency ultrasound (US) with photoacoustic imaging (PAI), bioluminescence and fluorescence imaging (optical imaging). The MIF provides state-of-the-art anatomical, functional and molecular medical imaging capabilities for animal models of human disease. The proposed equipment will add new capabilities to the assortment of MIF imaging equipment which will benefit a number of users throughout NIH. The objective is to acquire a new ultrafast Doppler ultrasound with the unique ability to perform functional ultrasound imaging (fUS), especially functional neuroimaging of brain. Purchase Description:� NAME BRAND or EQUAL Name Brand: Iconeous One Recently, a new technique has been developed that greatly increases the usefulness of Doppler ultrasound to changes in capillary blood flow.� Ultrasonic plane waves transmitted at ultrafast frame rates has been shown to highly increase Doppler ultrasound sensitivity to blood flows in small vessels in rodents. This ultrafast Doppler ultrasound can measure blood variations in a number of tissues including the brain where changes in blood flow are directly related to changes in neural activity. Thus, Ultrafast Doppler US, referred to as functional US, is rapidly becoming an important preclinical imaging technique. It has unprecedented high spatio-temporal resolution, deep penetration, high sensitivity and portability which makes it unique for functional studies on rodents.� Salient Characteristics: The NIH Mouse Imaging Facility (MIF) is seeking a system capable of functional Ultrafast Doppler US. The requirements include: Demonstrated ability to measure changes in blood flow using power Doppler at 100 micron spatial resolution and 10 msec temporal resolution from a single slice. Ability to make three dimensional images over the entire mouse or rat brain within 10 sec.� Capabilities to do this faster with emerging three dimensional techniques should be an option. Demonstrated ability to measure blood flow changes in regions of the rodent brain during changes in neural activity. It is preferred to have software that enables calculation of an activation map in real time. The software should be capable of calculating functional connectivity maps. Capabilities for angiography.� It is preferred to be able to use single particle tracking to reconstruct the entire vasculature in addition to direct imaging of larger vessels. There should be a cerebral positioning system to know where the US data is coming from with respect the rodent brain. Device should be mobile so it can be integrated with other imaging modalities or different behavioral apparatus. � Anticipated Delivery Period: �Within 12 months �after receipt of order (ARO) Capability Statement /Information Sought Contractors that believe that they possess the ability to provide the required equipment, should submit documentation on their ability to meet each of the project requirements in the response. The Contractor should directly and specifically state in the, capabilities statement, which project requirements can be meet and/or supplied. The Contractor must also provide the following; DUNS number, organization name, address, point of contact, and size and type of business (e.g., 8(a), HubZone, etc., pursuant to the applicable NAICS code); Identify where equipment and parts are manufactured; identify if the proposed equipment is available on GSA; and Provide any other information that may be helpful in developing or finalizing the acquisition requirements. The information submitted must be in and outline format that addresses each of the elements of the project requirement and in the capability statement /information sought paragraphs stated herein. A cover page and an executive summary may be included but is not required. The response is limited to two (2) page limit. The 2-page limit does not include the cover page or executive summary. The response must include the respondents' technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses. All responses to this notice must be submitted by the closing date and time of this announcement and must reference the Notice ID. Facsimile responses are NOT accepted. Responses must be submitted electronically to Kristina Jenkins, Contracting Officer, at kristina.jenkins@nih.gov Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work.
- Web Link
-
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- Record
- SN06042532-F 20210626/210624230124 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
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