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SAMDAILY.US - ISSUE OF NOVEMBER 18, 2020 SAM #6929
SOURCES SOUGHT

A -- Global Metabolomics on Fetal Liver

Notice Date
11/16/2020 12:15:02 PM
 
Notice Type
Sources Sought
 
NAICS
541715 — Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
 
Contracting Office
USDA ARS PA AAO ACQ/PER PROP FORT COLLINS CO 80526 USA
 
ZIP Code
80526
 
Solicitation Number
12805B21Q0018
 
Response Due
11/19/2020 12:00:00 AM
 
Archive Date
12/04/2020
 
Point of Contact
Diane Gamboa, Phone: 575-646-3460
 
E-Mail Address
diane.gamboa@usda.gov
(diane.gamboa@usda.gov)
 
Description
The United States Department of Agriculture (USDA), U.S. Meat Animal Research Center (USMARC), has a requirement for Global Metabolomics on Fetal Liver in Clay Center, NE. The NAICS Code is 541715. In response to this sources sought please submit information on your company's capabilities to provide this service. Please also provide information on whether your company is a small or large business in accordance with the NAICS code listed. The Government acknowledges that responses to this sources sought are not binding offers. The information obtained will assist in our market research and future solicitation processes.� The purpose of this sources sought is solely to obtain information and sources for our future requirement. Background: Scientists are developing scientific information and new technology to solve high priority problems for the U.S. beef, sheep, and swine industries. As part of the effort, they require global metabolomics using UHPLC-MS/MS in positive and negative ion mode on fetal liver samples to assess the effects of maternal mineral and energy supplementation during early pregnancy on fetal liver metabolism. Technical Requirements/Tasks:��Non-targeted UPLC-MS using multiple analysis methods to cover a diverse class of metabolites and provide the following analysis: Sample Preparation Multiple Analysis methods including: UHPLC-MS/MS(+ESI)1, UHPLC-MS/MS(+ESI)2, UHPLC-MS/MS(-ESI), UHPLC (HILIC)-MS/MS. A relative concentration profile of all structurally named small-molecule entities, which can include both endogenous compounds, xenobiotics, and their metabolites, extracted from the samples and detected by an HD4 Global Metabolomics platform. Coverage depth up to 1000 to 25000 metabolites/samples A statistical analysis of the resulting data, which consists of univariate significance tests (t-tests and ANOVA). Summary biochemical interpretation of selected, statistically significant metabolites provided in a Word report. An outline of the analytical methods. Access to downloadable study deliverables. Access to data analysis and visualization tools that allow for further data exploration. Publication ready tables and figures.
 
Web Link
SAM.gov Permalink
(https://beta.sam.gov/opp/8ea30aadd89a463a9af6c3bb141e3a86/view)
 
Place of Performance
Address: Clay Center, NE 68933, USA
Zip Code: 68933
Country: USA
 
Record
SN05854085-F 20201118/201116230141 (samdaily.us)
 
Source
SAM.gov Link to This Notice
(may not be valid after Archive Date)

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