SPECIAL NOTICE
99 -- NanoLC
- Notice Date
- 9/22/2020 7:48:05 AM
- Notice Type
- Special Notice
- Contracting Office
- NATIONAL INSTITUTES OF HEALTH OLAO BETHESDA MD 20892 USA
- ZIP Code
- 20892
- Solicitation Number
- NIH-OLAO-OD3-NOI5765474
- Response Due
- 9/24/2020 9:00:00 AM
- Archive Date
- 10/09/2020
- Point of Contact
- Candis Pelham, Phone: 3018279618, Anne Mineweaser, Phone: 3018277683
- E-Mail Address
-
candis.pelham@nih.gov, anne.mineweaser@nih.gov
(candis.pelham@nih.gov, anne.mineweaser@nih.gov)
- Description
- The National Institutes of Health intends to negotiate on a sole source basis with Evosep One. The Laboratory of Retinal Cell & Molecular Biology, NEI, requires a robust nanoscale Liquid Chromatography (nanoLC) system for high resolution mass spectrometry (MS) proteomics applications. This must be accessible to users of a wide range of technical proficiency. Despite its extremely high sensitivity, nanoLC is well-known for being a technically troublesome and demanding technique. Its high degree of complexity means that an extraordinary amount of troubleshooting often is required to make it work and this impacts its reproducibility and reliability. Much of this difficulty resides in the sequential use of extremely high-pressure pumps, extremely narrow columns and extremely low flowrate (mostly below 1 microliter/minute). All of these combined make nanoLC systems prone to blockage and downtime. Repeated downtime leads to variability and reduced reproducibility and the possibility of cross-contamination. Cross-contamination is an especially serious issue when the samples to be analyzed are so small. Therefore, an ideal system will also have enhanced measurement reproducibility and minimized cross-contamination. This can be accomplished by automating purification so that the steps of manually eluting samples, drying them down, and resuspending them are completely omitted. This is a novel approach only recently realized. Responses The proposed acquisition action is for items and services for which the Government intends to solicit and negotiate with only one source under the authority of FAR 13.106-1 (b). �If you believe you can provide the items or services requested, all responsible sources may submit a capability statement, which shall be considered by the agency, to the Contracting Specialist, Candis Pelham, at� candis.pelham@nih.gov ��referencing notice number NIH-OLAO-OD3-NOI5765474 on September 24, 2020.� A determination by the Government not to compete this proposed contract acquisition based upon responses to the notice is solely within the discretion of the Government.� Information received will normally be considered solely for the purpose of determining whether to conduct a competitive procurement. This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed. Information provided will be used to assess tradeoffs and alternatives available for the potential requirement and may lead to the development of a solicitation. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. Any solicitation resulting from the analysis of information obtained will be announced to the public in Federal Business Opportunities in accordance with the FAR Part 5. However, responses to this notice will not be considered adequate responses to a solicitation.� No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).
- Web Link
-
SAM.gov Permalink
(https://beta.sam.gov/opp/2dd55ca6d78f4977b7040bf543ca4038/view)
- Place of Performance
- Address: Bethesda, MD 20892, USA
- Zip Code: 20892
- Country: USA
- Record
- SN05806741-F 20200924/200922230208 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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