SPECIAL NOTICE
65 -- Callegari SRL Stress Analyzers and Test Kits
- Notice Date
- 8/17/2020 12:29:00 PM
- Notice Type
- Special Notice
- NAICS
- 334510
— Electromedical and Electrotherapeutic Apparatus Manufacturing
- Contracting Office
- W4PZ USA MED RSCH ACQUIS ACT FORT DETRICK MD 21702-5014 USA
- ZIP Code
- 21702-5014
- Solicitation Number
- W81XWH200052
- Response Due
- 9/1/2020 11:00:00 AM
- Archive Date
- 09/16/2020
- Point of Contact
- Christopher L. Cook, Phone: 3016192640
- E-Mail Address
-
christopher.l.cook68.civ@mail.mil
(christopher.l.cook68.civ@mail.mil)
- Description
- This notice announces the intent by the U.S. Army Medical Acquisition Activity (USAMRAA), 820 Chandler St, Fort Detrick, Maryland, 21702, to award a sole source contract to Callegari SRL under the statutory authority 13.106-1(b)(1). This contract is for the purchase 2 Callegari Centrifuges and approximately 2,500 FORT test kits and 2,500 FORD Test Kits for use at the US Army Research Institute of Environmental Medicine (USARIEM). During Basic Combat Training (BCT), musculoskeletal injury (MSKI) rates of up to 40% have been reported in men, and up to 67% in women. Due to the incidence and profound effects of MSKIs on Soldier health and performance, methods to identify recruits at high risk of injury would have significant impact on Soldier health and retention as well as reduce costs associated with MSKIs. The longitudinal monitoring of oxidative stress in military recruits may provide quantitative identification of individuals in various states of fatigue. Importantly, until recent breakthroughs in technology, successful application of oxidative stress biomarker monitoring has been hindered by poor repeatability of in-the-field testing tools and the challenge of rapid turnaround of results to understand whether changes are of physiological importance. Notably, these issues have been addressed by two recently developed point-of-care tests that are able to measure oxidative stress in-the-field.� The Free Oxygen Radical Test (FORT) is an indirect measure of reactive intermediary by-products of in vivo lipid, protein and nucleic acid oxidation (hydroperoxides), with higher FORT results demonstrating higher levels of hydroperoxides in the blood. The Free Oxygen Radical Defense test (FORD) is an indirect measurement of antioxidant capacity. Higher FORD results demonstrate greater antioxidant capacity. Both tests are manufactured by Callegari Srl (Parma, Italy) and the methodology established in administering these tests as well as the tests themselves are currently the only option established in the scientific literature for assessing oxidative stress in a point of care (under 5 minutes per test) manner using equipment that is suitable for in-the-field testing. The FORT and FORD reagents have been developed to be processed by the CR3000 blood analyzer and centrifuge 6000 (Callegari Srl, Parma, Italy). The CR3000 has a specific software with implemented algorithms and calibration curve developed by Callegari with the chemistries so only while testing with the CR3000 can you obtain the results of the FORD and FORT tests. The centrifuge 6000 is unique in that it can spin difference shapes and sizes of sample tubes (both square cuvettes and conical tubes) simultaneously. Only following the specific testing procedures provided by the manufacturer and using the above listed devices and reagents can the operator obtain the values of the free oxygen radicals and antioxidants concentration that may be then analyzed and compared with the reference values in the existing literature. Moreover, because frequent measures of oxidative stress must be taken to determine whether it is predictive of illness or injury in the military environment, assays must have excellent reliability. As mentioned above, the FORT and FORD tests are the only point-of-care tests designed to measure oxidative stress that have demonstrated excellent reliability. If these tests/reagents and equipment cannot be purchased we will not be able to deliver on the scientific findings promised in a DHP funded research proposal which is� part of a larger on-going research study entitled The Ariem Reduction in Musculoskeletal Injury Study. This research is being conducted by scientists at the US Army Research Institute of Environmental Medicine and has received approval from the US Army Training and Doctrine Command, Center for Initial Military Training. �An award will be issued on a sole source basis. The North American Industry Classification System (NAICS) for this requirement is 334510 and the size standard is 1,250.� This announcement fulfills the synopsis requirements under FAR 5.102(a)(6) and 5.203(a). USAMRAA intends to award a contract no sooner than 15 days after publishing this synopsis. This Special Request for Information is not a request for competitive quotes. Information received in response to this notice will be considered solely for the purpose of determining whether a competitive procurement is in the best interest of the Government. If no written responses are received by the expiration date listed in this notice, which reflects at least fifteen (15) days after the publication of this notice, the award will be issued as sole source. All questions and responses concerning this notice shall be emailed to Mr. Christopher L. Cook �at christopher.l.cook68.civ@mail.mil.�
- Web Link
-
SAM.gov Permalink
(https://beta.sam.gov/opp/d82c5ab6fa2244bc988826c38c34b67a/view)
- Place of Performance
- Address: Natick, MA 01760, USA
- Zip Code: 01760
- Country: USA
- Zip Code: 01760
- Record
- SN05760436-F 20200819/200817230200 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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