SPECIAL NOTICE
99 -- DNA Analysis: Infinium MethylationEPIC BeadChip Kit (96 samples)
- Notice Date
- 7/6/2020 7:45:37 AM
- Notice Type
- Special Notice
- NAICS
- 325413
— In-Vitro Diagnostic Substance Manufacturing
- Contracting Office
- NATIONAL INSTITUTES OF HEALTH
- ZIP Code
- 00000
- Solicitation Number
- HHSNIllumina07062020
- Response Due
- 7/20/2020 8:00:00 AM
- Archive Date
- 08/04/2020
- Description
- DESCRIPTION: The National Institutes of Health - NICHD intends to procure the services of a contractor to provide Infinium MethylationEPIC BeadChip samples targeting >850k methylated CpGs in promoter, gene body, and enhancer regions for genome wide methylation. �This is a continuation of a previous project where Illumina kits were used by the Lab and more DNA analysis and sample sequencing is needed. The aim of the project is to identify potentially chronic, heavy alcohol consumption is associated with differential DNA methylation patterns. Alcohol dependence (ALC) is a chronic, relapsing disorder that increases the burden of chronic disease and significantly contributes to numerous premature deaths each year. DNA methylation, an important type of epigenetic modification in humans, participates in crucial cellular processes, Several platforms have been developed to study genome-wide DNA methylation. Many investigators in the field have chosen the Illumina Infinium HumanMethylation microarray for its ability to reliably assess DNA methylation following sequencing sodium bisulfite conversion. and so it is important that all subjects be sequenced using the same DNA methylation platform.� HumanMethylation targeting >850k methylated CpGs in promoter, gene body, and enhancer regions for genome wide methylation studies and can only be sourced from the manufacturer, Illumina, Inc. This proposed procurement is for a service for which the government intends to solicit and negotiate on a sole source basis to Illumina Inc., located at� 5200 Illumina Way San Diego CA 92122-4616. In order to comply with the requirements in this Special Notice, the responses should be based on our interpretation of the general requirements provided below. Note 22. The proposed contract action is for a continuation of previous services for which the Government intends to solicit and negotiate with only one source under the authority of FAR 6.302. Interested persons may identify their interest and capability to respond to the requirement or submit quotations. This notice of intent is not a request for competitive quotes. However, all quotes received within the time and date of publication of this ""Special Note 22"" will be considered by the Government. A determination by the Government not to compete with this proposed contract based upon responses to this notice is solely within the discretion of the Government. Information received will normally be considered solely for the purpose of determining whether to conduct a competitive procurement. HOW TO RESPOND: In order to compete for this project, interested parties must be registered in the Central Contracting Registration and submit a price quotation by 3:00 pm, ET, July 9th 2020. Offerors may either submit one copy of the quote to MOE FILALI by mail or preferably via email. Electronic transmissions to Moe.Filali@nih.gov are preferable but must be timely. It is the responsibility of the Offeror to ensure the proposal is received by the date and time shown above. The following Federal Acquisition Regulations clauses are incorporated by reference: FAR 52.212-3, Offeror Representations and Certifications-Commercial Items (Mar 2005), 52.212-4 (Sept 2005), 52.212-5, Contract Terms and Conditions Required to Implement Statutes of Executive Orders-Commercial Items (Aug 2006). (6)(i) 52.222-26, Equal Opportunity (Apr 2002) (E.O. 11246). (18) 52.222-35, Equal Opportunity for Special Disabled Veterans, Veterans of the Vietnam Era, and Other Eligible Veterans (Dec 2001) (38 U.S.C. 4212). (19) 52.222-36, Affirmative Action for Workers with Disabilities (Jun 1998) (29 U.S.C. 793). (20) 52.222-37, Employment Reports on Special Disabled Veterans, Veterans of the Vietnam Era, and Other Eligible Veterans (Dec 2001) (38 U.S.C. 4212). (31) 52.232-33, Payment by Electronic Funds Transfer-Central Contractor Registration (Oct 2003) (31 U.S.C. 3332). Primary Point of Contact: MOE FILALI Contracting Office Address: � NIH/NICHD Office of Acquisitions 6710B Rockledge Drive, Room 1145D Bethesda, MD 20817 (w) 301.827 7737 Moe.filali@nih.gov � Attachments/Links Download All Attachments/Links
- Web Link
-
SAM.gov Permalink
(https://beta.sam.gov/opp/68f7c077892e4d1f9b77796601adb4fb/view)
- Place of Performance
- Address: San Diego, CA 92122, USA
- Zip Code: 92122
- Country: USA
- Record
- SN05711797-F 20200708/200706230146 (samdaily.us)
- Source
-
SAM.gov Link to This Notice
(may not be valid after Archive Date)
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