SOLICITATION NOTICE
B -- Univ of Indiana Syphilis Project
- Notice Date
- 7/24/2018
- Notice Type
- Presolicitation
- NAICS
- 541990
— All Other Professional, Scientific, and Technical Services
- Contracting Office
- Department of Health and Human Services, Centers for Disease Control and Prevention, Procurement and Grants Office (Atlanta), 2920 Brandywine Road, Room 3000, Atlanta, Georgia, 30341-4146
- ZIP Code
- 30341-4146
- Solicitation Number
- 75D301-18-Q-68961
- Archive Date
- 8/18/2018
- Point of Contact
- KIMBERLY GOLDEN, Phone: 7704882672
- E-Mail Address
-
IXM9@CDC.GOV
(IXM9@CDC.GOV)
- Small Business Set-Aside
- N/A
- Description
- NOTICE OF INTENT TO AWARD SOLE SOURCE The Centers for Disease Control and Prevention (CDC), Centers for Disease Control and Prevention Division of Vector Borne Diseases intends to award a sole source firm-fixed price services contract to Trustees of Indiana University located at 980 Indiana Ave Room 2232, Indianapolis, IN 46202. The statutory authority for this sole source acquisition is 10 U.S.C. 2304 (c) (1) in accordance with FAR Part 6.302-1- only one responsible source and no other supplies or services will satisfy the agency requirement. The government has a need for a follow-on contract to extract data for the Syphilis Stillbirth Study. SECTION 1 - BACKGROUND Congenital syphilis elimination is one of the 4 key strategic priorities in the Division of STD Prevention (DSTDP) at the Centers for Disease Control and Prevention (CDC). Women untreated for syphilis during pregnancy are subject to adverse outcomes such as stillbirth, spontaneous abortion, and serious sequelae of syphilis to the newborn. CDC and the American College of Obstetrics and Gynecology (ACOG) have long recommend syphilis screening for all pregnant women at their first prenatal visit. Additional syphilis testing at a gestational age of 28 weeks (during third trimester) and at the time of delivery may be warranted for women at elevated risk and women living in communities with a high prevalence of syphilis. In addition, CDC further recommends that if any woman delivers a stillbirth (defined as a fetal death at 20 weeks of gestation or more), she should be tested for syphilis. Routine screening of newborn sera or umbilical cord blood is not recommended. However, assessing overall adherence to CDC and ACOG recommended guidelines for prenatal syphilis testing for all pregnant women and syphilis testing after delivery for women with stillbirth is challenging, because many previous studies have used claims data that lack laboratory results, treatment information, and detailed clinical information. One previous study using commercial and Medicaid claims data has shown that about 61.7% of Medicaid-insured women and 66.0% of commercially insured women had prenatal syphilis testing. At the time of stillbirth, Medicaid-insured and commercially insured women had similar rates of syphilis testing (6.5% vs 9.3%), placental examination (61.6% vs 57.8%), and complete blood count (31.9% vs 37.6%). Autopsies were too infrequent to be reported. Approximately34.6% of Medicaid insured women and 29.7% of commercially insured women with a stillbirth had no syphilis testing, either prenatally or at the time of stillbirth. The primary result from another study conducted by the Regenstrief Institute also showed that prenatal syphilis testing was about 57% among women who had stillbirth. CDC researchers and DSTDP leadership have concerns about the lack of information found in administrative claims data, such as missing information for inpatient services, including STD testing or complete blood count (instances where the services may have been performed but which are not listed in the claims data). To have a better understanding of prenatal syphilis testing among women with stillbirth and to assess the completeness of administrative claims data, a study that reviews medical charts is required. More specifically, the study requires the use of a dataset that includes not only medical encounters, but also medical and prescription claims and lab tests, as well as completed medical charts. The key component of this contract will be the medical chart reviews among women with stillbirths to definitively determine if a woman received syphilis screening after stillbirth. The Indiana Network for Patient Care (INPC) at the Regenstrief Institute is a well-established, population-based electronic medical record system that provides a unique opportunity to assess guideline adherence, because INPC includes electronic health records, lab tests, clinical encounters, and medical and prescription claims that can be linked to local STD clinic data, state STD surveillance data, and state birth registry data. SECTION 2 - PURPOSE The purpose of this action is to secure the services of the Regenstrief Institute to extract INPC data and its linked data sufficient to:1) identify women with stillbirth, 2) assess prenatal care and prenatal syphilis testing practices for all women with stillbirth, 3) assess syphilis testing practices after delivery for women with stillbirth, 4) assess prenatal syphilis testing results (nontreponemal and treponemal ), 5) review medical charts for syphilis-related services for all women who had any reactive syphilis test results or were treated for syphilis and for a sample of those with stillbirth who did not have a reactive syphilis test or syphilis treatment. The study period will cover 3 years (2014-2016) for these special populations. SECTION 3 - SCOPE OF WORK INPC is one of the largest medical data warehouses, with 660 million distinct observations that have been collected continuously since 1973. This system is considered one of the best medical record systems in the world, and is the only functional population-based health information exchange (HIE) in the United States. INPC data are frequently extracted by expert data analysts at the Regenstrief Institute to study a variety of diseases, and provide a unique opportunity to establish population-based cohorts within a well-established health system. In addition, the datasets have been linked to local STD clinic data, state STD surveillance data, and state birth registry data. Previous studies have showed that determination of syphilis cases and date of delivery are critical and challenging tasks when using only medical claims data without additional data sources. The linked data provide accurate date of delivery for women from state birth registry data, as well as STD morbidity and detailed treatment information from state STD surveillance data. Under this contract, the contractor will extract data from this well-established data system and review medical charts to answer research questions on syphilis testing for women with stillbirth. SECTION 4 - TASKS TO BE PERFORMED The vendor shall perform the following tasks to complete the required data analysis: A. With a database for women with stillbirth that can be linked to lab data, encounter data, and medical claims data to estimate prenatal syphilis testing, the vendor shall classify women with stillbirth into two groups: 1) those who had reactive syphilis results or were treated syphilis during pregnancies, and 2) all others who had no reactive syphilis tests. B. Review medical charts for all women in the 1st group. C. If the number of women in the 2nd group is similar to the number of women in the 1st group, then review medical charts for all women in the 2nd group; if the number of women in the 2nd group is larger than the number of women in the 1st group, then randomly select a sample of women or a stratified sample based women's age and clinic settings that matched with women in the 1st group for medical chart review. The sample size should be the same, double, or triple as the number in the 1st group as a matched cohort, according to the number of women in the 1st group. D. Review medical charts and create a database based on medical chart review for women who had stillbirth. The database should include insurance type, smoking status, alcohol use, drug use, gestation length, number of prenatal visits, prenatal syphilis status and the time of prenatal syphilis testing, placental examination, complete blood count, and autopsy. E. Analyze data and report of syphilis testing among pregnant women F. Analyze data and report of syphilis testing among women with stillbirth G. Collaborate on preparation of two manuscripts reporting the findings of the analysis for publication in a peer-reviewed journal. The period of Performance for this project is from September 1, 2018-March 31, 2019. The NAICS code is 541990 All Other Professional, Scientific and Technical Services with a size standard of $15 Million dollars. No solicitation will be posted to FedBizOpps. We will only issue a solicitation to Colorado State University. Colorado State University is the only source available to provide this equipment that meets mission critical requirements. This notice of intent is not a request for proposal. A determination to compete this procurement based on response to this notice is solely within the discretion of the Contracting Officer. Interested parties who believe they possess the capability to satisfy this requirement should submit a capability statement demonstrating their ability to meet this requirement. All responses must be sent in writing to Ms. Kimberly Golden via email to ixm9@cdc.gov using solicitation number 75D301-18-Q-68961 in the subject line, no later than 10:00 am Eastern Time, August 8, 2018. Place of Contract Performance: Centers for Disease Control and Prevention Division of STD Prevention Centers for Disease Control and Prevention Atlanta, Georgia 30333
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/CDCP/PGOA/75D301-18-Q-68961/listing.html)
- Place of Performance
- Address: Centers for Disease Control and Prevention, Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, Atlanta, Georgia, 30333, United States
- Zip Code: 30333
- Zip Code: 30333
- Record
- SN05003975-W 20180726/180724230744-67d5c3d0600d1da74aa071cb47c0b43d (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
| FSG Index | This Issue's Index | Today's FBO Daily Index Page |