SOURCES SOUGHT
66 -- System Components for 7T Small Animal MRI System (NINDS)
- Notice Date
- 7/16/2018
- Notice Type
- Sources Sought
- NAICS
- 334510
— Electromedical and Electrotherapeutic Apparatus Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, 6001 Executive Boulevard, Room 4211, MSC 9559, Bethesda, Maryland, 20892-9559, United States
- ZIP Code
- 20892-9559
- Solicitation Number
- NIHDA201800342
- Archive Date
- 8/7/2018
- Point of Contact
- Jeffrey Brown, Phone: 301.827.5852, Kenneth Goodling, Phone: 301.443.6677
- E-Mail Address
-
jeffrey.brown@nih.gov, kgoodlin@nida.nih.gov
(jeffrey.brown@nih.gov, kgoodlin@nida.nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Introduction: This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement. This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. Background: T he Cerebral Microcirculation Section of the Laboratory of Functional and Molecular Imaging is focused on understanding how brain cells communicate with blood vessels to ensure that the brain tissue is continuously supplied with adequate amounts of blood. For this, research in CMS employs small animal models, including rodents and small primates, and a state-of-the-art 7T small animal MRI system that allows the acquisition of anatomical and functional magnetic resonance imaging (MRI) data of the brain of the animals. The existing MRI system was installed and commissioned in 2005. It has been in operation ever since. The system was originally fitted with a set of gradient amplifiers from Copley Controls, Inc., model C700, and with a gradient set with integrated shims from Resonance Research, Inc., model BFG-270/150-S-7. The gradient set is the device that provides linear variation of the main magnetic field B0 to allow spatial encoding of the sample inside the magnet, so that MR images can be obtained. The gradient set operates when currents generated in the gradient amplifiers are fed into each of the three coils of the gradient set. The original set of gradient amplifiers (Copley C700) has been in operation since 2005 and is at the end of its useful life. This existing set of gradient amplifiers has failed multiple times in the past several years, and everytime they fail, our MRI system goes down and we have a significant amount of downtime until a replacement unit comes from the manufacturer. NINDS needs to replacement units for our existing C700 amplifiers, and NINDS need to procure a brand new set that will allow NINDS to continue operation of our small animal 7T MRI system. Project requirements: 1. MRI Gradient Power Amplifiers: 2. MRI Gradient Set: 3. RF Filters: 4. Temperature and Water Flow Monitoring System: 5. Water Chiller-Circulator: Salient characteristics 1. MRI Gradient Power Amplifiers: a. General characteristics: The Gradient Power Amplifiers consist of 3 identitical modules capable of supplying the gradient set with current pulses and waveforms typical of MRI pulse sequences. The 3 modules are fed by a power supply, and the entire set is integrated into a single rack and cooled by a cooling system connected to the chilled water supply. b. Functional Specifications: At a minimum, the MRI gradient power amplifiers must meet the minimum set of specifications/performance standards: i. Isolated power supply - Mains: 380-480Vrms ±10%, 50/60Hz - Mains switch included - Power Factor Correction (PFC): unity power factor & low harmonics - Maximal mains power: 32kVA - Programmable bus voltage: 600Vdc...990Vdc. ii. Output performance - Output voltage (at Vbus max): ±940V - Output current: 630A peak, 230A rms - Maximum continuous output power: 5.3kW per axis, 13kW for all three axes - Tunable Load range: 220μH – 4.7mH iii. Output accuracy - High precision integrated current sensors - Bandwidth >10kHz - Settling time: error<1% after 100μs, <0.4% after 150μs, <0.1% after 250μs - Initial offset: negligible (auto-zero) - Drift: typical offset 5mA/°C, typical gain 10ppm/°C - Propagation delay: <70μs - Total harmonic distortion: <0.4% at 230A rms/200Hz, <0.8% at 230A rms/1kHz iv. Control / communication / monitoring - Differential analog current set-point - RS422 control interface - Ethernet service interface - Synchronous operation via distributed clock - Digital control loop tuning - Analog monitoring: output current,current set-point, output voltage, bus voltage, current error v. Error protection & diagnostics - Built in self-test - Advanced diagnostics via control interface - Front panel LCD and status LEDs per module - Fault tolerant fans with tacho - Output overcurrent protection (peak & RMS) - Mains error detection - Water leakage detection - Integral temperature protection vi. Mechanical - Cabinet size: no larger than 615x825x1800mm (WxDxH) - Liquid cooled vii. Regulatory & environmental - Reliability: MTBF > 50khr. - Lifetime: >10 years - RoHS & REACH compliant 2. MRI Gradient Set: a. General characteristics: The MRI Gradient Set consists of a shielded, MRI-compatible set of 3 gradient coils (X, Y and Z) with an integrated set of shim coils and integrated cooling. The gradient set will operate inside CMS’s existing small-animal 7T/30 cm magnet, and will interface with the MRI console and Gradinet Power Amplifiers via a set of filters specified in item #3 below. b. Functional Specifications: At a minimum, the MRI gradient set must meet the minimum set of specifications/performance standards: i. Gradient set dimensions: OD: <300 mm; ID: >170 mm. ii. Gradient strength: minimum of 450 mT/m @ 500 A maximum current (gain 0.9 mT/m/A) iii. Maximum Operating Current/Voltage: 500 A/1000 V iv. Water cooling: minimum 6 lpm v. Maximum weight: 250 kg vi. Integrated temperature sensors : minimum of 6 sensors vii. Min. heat dissipation: 3.5 kW for ΔT=25 ºC viii. Maximum Rise Time: 120 μs to peak gradient in all 3 axes. ix. Minimum Slew rate: 4000 T/m/s x. Minimum RMS current, all axes simultaneously: 100 A xi. Linearity for a 100 mm DSV X/Y: ±3% Z: ±2.5% xii. Shielding quality: > 99 % xiii. Orthogonality: 90 ± 1 degree xiv. Residual Eddy Currents (before pre-emphasis): < 0.5 % measured 1ms after 20ms trapezoidal pulse xv. Integrated Shim System with a minimum of 12 shim channels rated at 10 A maximum DC current and the following minimum strengths in Hz/cm 2 /A: Z2, 180; Z3, 20; ZX/ZY, 150; C2/S2, 100; Z2X/Z2Y, 20; ZC2/ZS2, 25; C3/S3, 10; xvi. Cable Connections: Compatible with BRUKER AV3 Schaultbau 2 connector. 3. RF Filters: a. General Characteristics: The RF filters are electronic devices that operate in a filter plate in the penetration panel that sits at the wall between the MRI console room and the magnet room. Their function is to prevent RF irradiation from passing from the console room to the magnet room, where it could interfere with image quality. These RF filters are critical elements when interfacing the gradient power amplifiers to the gradient set. b. Functional Specifications: At a minimum, the RF filters must meet the minimum set of specifications/performance standards: i. Penetration panel material: stainless steel ii. Low-pass cutoff frequency of 30MHz with minimum attenuation of -100 dB iii. Filters: high capacitance, 500A; 2000V; 900 A peak iv. Number of channels: 3 dual filters v. Cooling of filters by forced air via AC fans 4. Temperature and Water Flow Monitoring System: a. General Characteristics: This is a monitoring/protection system that fits inside a standard 19” wide sub-rack chassis and monitors the current operating temperature of the RF filters, of the gradient set and integrated shims, and of the gradient chiller. If any of the operating temperatures exceed their setpoint, the monitoring system sends an interlock signal to the MRI console preventing its use, so that the gradient set and RF filters are protected from being damaged by over temperature conditions. b. Functional Specifications: At a minimum, the Temperature and Water Flow Monitoring System must: i. System continuously reads temperature of the gradient RF filters and of the integrated gradient/shim set. temperature monitoring system ii. System features a 6 channel RTD temperature scanner/monitor iii. System features an RS-232 programming cable iv. System features an interlock cable able to connect to the existing MXW shim power supply v. Water flow switch (external water supply required) vi. System features monitoring of water temperature and flow of the gradient chiller vii. System features interlock cables to the gradient chiller viii. System allows Emergency shutdown of the console in case of over temperature. 5. Water Chiller-Circulator: a. General Characteristics: The Water Chiller-Circulator is a machine that circulates chilled water to keep the gradient set operating temperature within an optimal range, preventing the gradient set from overheating during its operation. b. Functional Specifications: At a minimum, the water chiller-circulator must have: i. An integrated cooling coil to keep water refrigerated ii. A circulator capable of pumping refrigerated water at a rate of 6 gallons per minute iii. Enough volume / heat capacity to dissipate in excess of 1KW of heat at constant temperature iv. Water Cooling Capacity of 20 Kilowatts minimum Warranty: One year warranty. Anticipated Period of Performance: Delivery within 6 months of award. Capability statement /information sought: Contractors that believe that they possess the ability to provide the required equipment, should submit documentation on their ability to meet each of the project requirements to the Contract Specialist. The Contractor should directly and specifically state in the, capabilities statement, which project requirements can be meet and/or supplied. The Contractor must also provide their DUNS number, organization name, address, point of contact, and size and type of business (e.g., 8(a), HubZone, etc., pursuant to the applicable NAICS code and any other information that may be helpful in developing or finalizing the acquisition requirements. The information submitted must be must be in and outline format that addresses each of the elements of the project requirement and in the capability statement /information sought paragraphs stated herein. A cover page and an executive summary may be included but is not required. The response is limited to two (2) page limit. The 2-page limit does not include the cover page or executive summary. The response must include the respondents’ technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses. All responses to this notice must be submitted electronically to the Contract Specialist. Facsimile responses are NOT accepted. The response must be submitted to Jeffrey E. Brown, Contracting Officer, at jeffrey.brown@nih.gov. The response must be received on or before July 23, 2018 at 12 pm, Eastern Time. Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization’s qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a presolicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDA-01/NIHDA201800342/listing.html)
- Place of Performance
- Address: Cerebral Microcirculation Section (CMS) of the Laboratory of Functional and Molecular Imaging (LFMI), 49 Convent Drive, Bethesda, Maryland, 20892, United States
- Zip Code: 20892
- Zip Code: 20892
- Record
- SN04993975-W 20180718/180716231421-276db462660d6fc3f3d8b6fe250a382d (fbodaily.com)
- Source
-
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