SPECIAL NOTICE
A -- PTSD Mouse Knockout Model Characterization
- Notice Date
- 7/2/2018
- Notice Type
- Special Notice
- NAICS
- 541380
— Testing Laboratories
- Contracting Office
- Department of the Army, U.S. Army Medical Research Acquisition Activity, U.S. Army Medical Research Acquisition Activity, Attn: MCMR-AAA, 820 Chandler Street, Frederick, MD 21702-5014, Maryland, 21702-5014, United States
- ZIP Code
- 21702-5014
- Solicitation Number
- W81XWH-18Q0202
- Archive Date
- 8/1/2018
- Point of Contact
- Michael E Baughman, Phone: 3016192315
- E-Mail Address
-
michael.e.baughman.civ@mail.mil
(michael.e.baughman.civ@mail.mil)
- Small Business Set-Aside
- N/A
- Description
- The contractor shall provide USACEHR with results of behavioral studies and histological analyses of transgenic and knockout mice, that have been generated as part of our laboratory based PTSD studies. The contractor shall conduct a battery of behavioral tests on the following groups of mice (n=8-16 per group): wild-type (C57/Bl6 strain) and 2 whole body gene knockout lines. These mice will be initially supplied by USACEHR and breeding will be carried out at the contractor's laboratory to attain sufficient numbers of mice for the testing and analysis. Following the behavioral tests, the same mice will be euthanized and brain and other tissues will be assessed using histological and neuroimaging techniques. In addition to the first 3 groups of mice, histological analysis will also be conducted on a transgenic mouse line (Ascl1-Cre/ERT2:ROSA) that will be generated at the contractor's laboratory by crossing the Ascl1-CreERT2 line (supplied by USACEHR) with the ROSA26 Cre-reporter line (supplied by contractor).
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/USA/USAMRAA/DAMD17/W81XWH-18Q0202/listing.html)
- Place of Performance
- Address: USACEHR, Fort Detrick, Maryland, 21702, United States
- Zip Code: 21702
- Zip Code: 21702
- Record
- SN04976948-W 20180704/180702230959-a8acfa8d78ce95f2dc7b542d8f73753d (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
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