DOCUMENT
66 -- Lab 45 Behavior Equipment - Attachment
- Notice Date
- 7/2/2018
- Notice Type
- Attachment
- NAICS
- 334516
— Analytical Laboratory Instrument Manufacturing
- Contracting Office
- Department of Veterans Affairs;Southeast Louisiana Veterans HCS;1555 Poydras Street;New Orleans LA 70112
- ZIP Code
- 70112
- Solicitation Number
- 36C25618Q9705
- Response Due
- 7/5/2018
- Archive Date
- 10/3/2018
- Point of Contact
- Debra James
- E-Mail Address
-
k
- Small Business Set-Aside
- Service-Disabled Veteran-Owned Small Business
- Description
- Lab 45 Behavior Equipment Southeast Louisiana Veterans Health Care System New Orleans, LA 70119 1. Department of Veterans Affairs Southeast Louisiana Veterans Healthcare System (SLVHCS) is seeking a Service Disabled Veteran Owned Small Business or Veteran Owned Small Business to provide, transport, install, configure, and training for all listed equipment to the to the SLVHCS. This acquisition is Set Aside 100% Service Disable Veteran Owned Small Business or Veteran Owned Small Business. INSTRUCTIONS TO SOURCES This is a Sources Sought Notice and is not a Request for Proposal (RFP). No solicitation is being issued at this time. This notice shall not be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Any information provided to the Government as a result of this Sources Sought Notice is voluntary. To reiterate, this is a Sources Sought Notice that is for planning purposes only and is intended to identify Service Disable Veteran Own Small Business or Veteran Owned Small Business who can support this requirement. INSTRUCTIONS to SOURCES FOR SUBMISSIONS Interested contractors shall submit a response to Debra James via email at debra.james3@va.gov. Responses are due no later than 7/5/2018 12:00pm Central Standard Time. Within your email please provide your capabilities statement and indicate if you can provide all items listed and instructions within this document along with delivery, installation, configuration, training, and manufacturer s warranty. Statement of Work SOW Lab 45 Behavior Equipment Southeast Louisiana Veterans Health Care System Research Service 11F New Orleans, LA 5/3/2018 1. PURPOSE 1.1 The overall purpose is to provide and configure equipment for the Veterinary Medical Unit at Southeast Louisiana Veterans Health Care System (SLVHCS) Research Building, P, 2400 Canal St, New Orleans, LA 70119.This equipment is requested to fulfill the Research mission. 2. SCOPE 2.1 The Contractor shall provide, transport, install, and configure all listed equipment. All products must meet all salient characteristics defined in this section. 2.2 All equipment and installation must meet manufacturers and VA specifications. 2.3 The Contractor shall furnish all supplies, equipment, facilities and services required for delivery and installation of the supplies and equipment. 2.4 The Contractor is responsible for any missing parts and components not included in order to carry out the installation. 2.5 SALIENT CHARACTERISTICS 2.5.1 Description: Alcohol/Nicotine Vapor Inhalation System for Rodents Qty: 3 ID#: Q20170425 Configured in Research building rooms: TBD Brand Name/ Model: La Jolla Alcohol Research, Inc. or Equal Brand URL: http://www.ljari.com/products/ Specifications/Salient Characteristics: Alcohol Vapor Inhalation Systems Rat and mouse alcohol inhalation systems include 4 alcohol and 4 air boxes, the cart that carries them, the complete delivery system and an air compressor. Please note that each box can house up to 3 animals, depending on their size. Also, we provide you with a divider that can be used to subdivide each box into 2 smaller compartments. This is particularly useful if, for example, you need to keep some animals separate but do not want to devote an entire box to each of them. A combined system for both rats and mice boxes is also available. Some important features of the La Jolla Alcohol Research Inc. alcohol inhalation system are as follows: The ability to measure alcohol concentration in any given chamber without opening the chamber and/or disturbing the animal(s). The ability to adjust alcohol delivery in order to achieve and maintain any desired BALs for any given time period. The ability to deliver different alcohol concentrations to, and therefore achieve different BALs in, each chamber. This allows investigators to run several experiments in parallel. The possibility to house rodents in the chambers with access to food and water. During this time, the animals can be exposed to alcohol either continuously or intermittently for hours, days or even weeks. This is simply achieved by programming the timer to turn the delivery system on and off at the specified time(s). The possibility to house animals equipped with indwelling cannulae in the periphery and/or the brain (including microdialysis cannulae). This allows investigators to deliver test substances and/or sample biological fluids while the animals are exposed to alcohol without handling or disturbing the animals in any way. The lids of the cages are equipped with holes that can be custom-made to fit any cannulae size, and that are plugged when not in use. Thus delivery of test substances and collecting of biological fluids can be done without opening the chambers, which protects the consistency of the environment. Once the delivery system has been set at the desired value, there is no need for laboratory personnel to remain with the animals while they are exposed to alcohol. Each cart holds eight chambers (4 alcohol and 4 air only). It can easily be wheeled from one room to another and does not require a dedicated space. Because each chamber is completely isolated, alcohol vapors do not escape to the surrounding environment. The size of the rats or mice cages is different in order to accommodate the characteristics of these two species in terms of weight and alcohol metabolism. We recommend that you do not use rat cages for use with mice or vice-versa because this will lead to very heterogeneous BALs. As both types of cages are controlled by the same delivery system, investigators who purchase both rats and mice cages can switch back and forth between these two species. They can also purchase additional cages to fit their research goals. Charts have been developed in male and female rats and mice of the strains most commonly used in alcohol research (rats: Sprague-Dawley, Wistar and Long-Evans; mice: BALB/c and C57BL/6J). These charts indicate the parameters of the delivery system as a function of the animals weights and the desired BALs. This takes the guesswork out of the experiments and while we recommend that BALs be measured in each investigator s set-up, the charts provide useful guidelines. 2.5.2 Description: Analox Alcohol Concentration Analyzer, Qty: 1 CONFIGURED IN RESEARCH BUILDING ROOMS: TBD Brand Name/Model: Analox URL: https://www.analox.com/analysers/am1/ or equal brand Specifications/Salient Characteristics: The AM1 analyser is used for Clinical Research applications and offers researchers into alcoholism a very fast method of obtaining results with small animal models. In addition the small sample size (5ul) enables real-time results to be obtained during experiments. After calibration with an appropriate standard, the single injection of sample is all that is needed to obtain a result and prepare the analyser for the next analysis. Sample injection via an accurate positive displacement pipette triggers the complete analytical cycle and a hard-copy result is printed within 20 seconds. 2.5.3 Description: Rat Operant Self-administration Boxes Qty: 32 Configured in Research building rooms: TBD Brand Name/ Model: Med Associates or equal Brand URL: http://www.med-associates.com/ Specifications/Salient Characteristics: Self-administration tests allow assessment of drug rewarding and drug-seeking behavior. Apparatus includes: Sound Attenuating Cubicle Standard Modular Operant Test Chamber with Modified Top for Rat Stainless Steel Grid Floor for Rat or Small Primate House Light for Rat Stimulus Light for Rat Retractable Lever Modular Pellet Dispenser for Rat, 45mg Pellet Receptacle, Trough Type SmartControl Drug Delivery Arm Assembly with 3/8 Gimbal Ring Syringe Pump Vascular Access Tether Kit for Rat Vascular Access Harness for Rat Shock system and cable Tabletop interface cabinet Dual cup liquid receptacle 2.5.4 Description: Behavioral monitoring system, orofacial pain test box QTY: 1 CONFIGURED IN RESEARCH BUILDING ROOMS: TBD Brand Name/ Model: Stoelting anymaze orofacial pain assessment device (OPAD) or equal brand URL: https://www.stoeltingco.com/anymaze/video-tracking/driven-products/opad.html Specifications/Salient Characteristics: The OroFacial Pain Assessment Device (OPAD) provides an automated measurement of hot or cold orofacial pain assessment in the trigeminal nerve in rats and mice. Using an operant behavior conflict paradigm, rodents voluntarily decide between receiving a reward or escaping an aversive stimulus. The OPAD begins to work when the animal touches and presses between dual peltier-controlled temperature elements to obtain a liquid reward. As the temperature (hot or cold) becomes aversive, the animal can withdraw. The OroFacial Software will automatically track, the number of licks, contact with elements, and amount of liquid consumed. Features Hot or Cold Temperature Control Objective Pain Assessment Operant Testing and Measures High Throughput Rackable System Up to 16 Cages with a Single Computer 4 ° to 75 °C Temperature Range Easy to Clean Easy USB Connection Designed for use with Mice and Rats Hardware The OPAD cage for either mice or rats is seated on a metal base that is easily cleaned. A metal rack is enclosed and can be removed and cleaned between animals. Animals are trained and tested in the cage; the reward bottle is positioned to allow access when simultaneously contacting the thermode with its orofacial region. The metal spout is connected to the data acquisition for recording each lick, in addition, contact with the thermode will record every touch and duration, and finally the amount (grams) of consumption from the reward bottle is also recorded. Each cage is easily attached to computer via USB port. Easy to clean Thermode adjustable Single cage for mice and rats LCD display Bottle can be moved easily Easy On/Off Software All of the data taken from the hardware will then be displayed and analyzed using a specialized OroFacial software, as a module of broader software package capable of analyzing multiple tests, such as Anymaze software. The software will display and track in real-time the following events: temperature changes and contacts with the thermode, licks and weight of the reward bottle. Following completion of the test, the OroFacial Software will display graphs and statistical analysis of the experiment(s); data can be downloaded to other software programs. The following functions should be available with the Orofacial Software: Set and change thermode temperature Automatically tracks licks, and touches to reward bottle & thermode Ability to ramp temperature during experiment Graphs and statistical analysis available Up to 16 cages with a single computer Easy to use interface and protocol set-up 2.5.5 Description: Hargreaves Thermal Nociception/ Plantar Paw Withdrawal/Tail flick Apparatus ID#: Plantar Test Apparatus QTY: 1 CONFIGURED IN RESEARCH BUILDING ROOMS: TBD Brand Name/ Model: IITC Plantar Analgesia Meter or equal brand URL: https://www.iitcinc.com/Plantar_tailflick.html Specifications/Salient Characteristics: A Plantar Analgesia Meter consists of a heat source (test head) that can be positioned under the paw of a rodent placed in a plexiglass box on glass platform. The test head slides under test subject, align the heat source via a guide light (idle state) by the attached, adjustable, angled mirror on test head to test subject and perform tests. The IITC Plantar Test and tail Flick Test Apparatus combination system all in one; is the only commercially available system of its kind. No need to purchase two separate systems, our combinations system enables researchers to perform both tests with this unique design. Testing properties of narcotic and stronger non-narcotic drugs on unrestrained mice and rats in plantar mode. Precise programmable digital control Humane cut-off feature Adjustable beam intensity in 1% increments room temperature to 250 degrees c. Manual override of all timer functions Alphanumeric readout All Functions and parameters entered via key-pad Heated glass option only from IITC Footswitch - RS232 - Printer output (standard) Software - USB - (optional) 2.5.6 Description: Tail Flick System ID#: QTY: 1 CONFIGURED IN RESEARCH BUILDING ROOMS: Brand Name/ Model: IITC or equal brand URL: Specifications/Salient Characteristics: The Tail Flick Test apparatus meter measures latency and/or temperature threshold when detecting properties of narcotic and strong non-narcotic drugs on mice and rats. A built-in Timer is automatically stopped when the animals tail flicks out of the beam of light, test result will be displayed on readout for viewing. An overhead halogen light source is in a constant ON (idle state). A pre-focused heat source supplies an area of 4X6mm stimulation to the tail. A built-in sensor in the tail groove detects the tail flick of the animal. The tail groove is a non-metallic material to avoid unnecessary conditioning of your animals; unlike other systems. If the animal does not flick their tail within the pre programmed cut-off time; the heat source shuts off automatically; avoiding tissue damage. Built-in timer displays the reaction time in 0.01 second increments. Control of system can be from either the front panel or supplied footswitch: Start, Stop and Reset of tests. The Tail flick test is the most frequently used analgesia test and together with the combination plantar/tail flick apparatus above provides an economic way to enable the plantar test while having 2 tail flick tests available for multiple investigators. 2.5.7 Description: Von Frey and Randall Selitto Mechanical Nociception Paw Withdrawal and Volume Apparatus ID#: 2393 QTY: 1 CONFIGURED IN RESEARCH BUILDING ROOMS: TBD Brand Name/ Model: IITC Trio Electronic von Frey Anesthesiometer/Randall-Selitto/paw volume apparatus or equal brand URL: https://www.iitcinc.com/trio_.html Specifications/Salient Characteristics: Electronic von Frey Aestehsiometer is used to assess mechanical allodynia with rigid tips (threshold) and the Supertips (flexible von Frey hairs) are used for sensory test on all test subjects from all animal test subjects and human studies. When studies call for pain threshold, rigid tips are used when measuring sensory threshold one of the 15 Supertips are used. The hairs are unique in design - each hair has a uniform tip of.8mm in diameter, eliminating the possibility of false readings that may occur due to the varying hair thickness when applied to test subject. The systems will allow you to measure, store and display your test readings in grams based upon the amount of pressure applied. Manually calculating results is no longer required with the IITC system. Testing is simple, choose one of the supplied tips place on probe tip; apply pressure probe to test subject, upon reaction the unit will The Randall-Selitto method assesses mechanical hyperalgesia and uses a hand held instrument to apply a force to the extremity of the test subjects. Live readings are provided of whatever force is applied at any moment with Peak and Hold showing the last maximum force applied during the test. Additional Pressure Applicators available. The paw volume apparatus assesses edema in inflammatory pain models. The trio combination of vonFrey, Randall-Siletto and paw volume allows economic use of a single analysis system for 3 tests 2.5.8 Description: Thermal hot/cold place preference system ID#: QTY: 1 CONFIGURED IN RESEARCH BUILDING ROOMS: TBD Brand Name/ Model: Bioseb 2-choice hot/cold preference test or equal brand URL: http://www.bioseb.com/bioseb/anglais/default/item_id=897_cat_id=20_Thermal%20Place%20Preference,%202%20Temperatures%20Choice%20Nociception%20Test.php Specifications/Salient Characteristics: This behavioral assay allows monitoring temperature nociceptive thresholds based on place preferences. It is an investigator-independent operant test that measures the reaction time of an animal (mouse or rat) exposed to a certain temperature. The "two Temperatures Choice Test" returns a nociceptive response without any action from the operator, indicating the sensitivity of the animal to the exposure to different stimulations (cold or heat). Operator-independent Operated on unrestrained, freely moving animals Automatic if using the optional software Windows 7/8 32/64bits compatible Transition lists can be managed or imported from xls/csv file Ability to resume an interrupted session Replay experimental videos, incl. animal detection Display and export results for custom time periods - tracking activity and detecting zone transitions Parameters measured include : Time spent in each temperature zone (abs. and %) Time of each zone trespassing Temperature of each zone Activity time of the animal (total or by zone) Distance run by the animal (total or by zone) 2.5.9 Description: Rotarod ID#: QTY: 1 CONFIGURED IN RESEARCH BUILDING ROOMS: TBD Brand Name/ Model: Columbus Instruments Rotamex-5 or equal brand URL: http://www.colinst.com/product-detail?pid=46 The rotarod tests the ability of rodents to maintain themselves upright on a rotating rod. Motor coordination is affected by many drugs. Animals are placed on a spindle within a lane sized to the subject under test. The operator may select accelerating or constant speed mode of operation as well as a slow speed waiting mode before acceleration takes place. Speed and acceleration rate are programmable. An animal fall is detected by infrared photo-cells which cross the space just above the spindle. Once all the photocells lose sight of the animal, the time is recorded. There are two diameters of easily interchanged rotating rods; one for mice and another for rats (see specs below for measurements). Rotamex-5 can communicate with computers when equipped with RS-232 Output option with Software: Software allows additional functions of the rota-rod. Programmed intervals for speed changes, even spinning direction, can be programmed into a specific protocol of the users design. With the photocells at the top, rather than the bottom, looping behavior can also be monitored; length of trial and number of loops. Data generated is in a CSV format to be easily opened by most statistical analysis programs. Features / Specifications Number of Exercise Lanes: 4 Rotarod Spindle Speed Range: 0 - 99.9 RPM Acceleration Increments: 0.1 RPM per second. to 20.0 RPM per second Mouse Spindle Dimensions: 3.0 cm x 9.5 cm Rat Spindle Dimensions: 7.0 cm x 9.5 cm Fall height From Rod center: 44.5 cm Unit Dimensions(LxWxH): 61cm X 56cm X 77cm Weight 27.5 kg Data Recorded: Running duration, Rotarod speed at time of fall, distance traveled Animal Detection Method: Scanning infrared beam(32) sensors monitor animals absence from rod assembly. Power Connections: 100 Vac to 240 Vac @ 50-60 Hz Auto configurable. Power Consumption: 70 Watts Fuse size: 3 amp slow blow Communication (optional): RS-232 to RS422(CIBUS) Multi drop. (Max of 64 devices) 2.7 DELIVERY AND INSTALLATION 2.7.1 DELIVERY 2.7.1.1 Contractor shall deliver all equipment to the Southeast Louisiana Veterans Health Care System (SLVHCS), Research Building, P, 2400 Canal St, New Orleans, LA 70119 beginning on August 17, 2018. 2.7.1.2 Deliver materials to job in manufacturer's original sealed containers with brand name marked thereon. 2.7.1.3 Package to prevent damage or deterioration during shipment, handling, storage and installation. Maintain protective covering in place and in good repair until removal is necessary. 2.7.1.4 Deliver specified items only when the site is ready for installation work to proceed. 2.7.1.5 Store products in dry condition inside enclosed facilities. 2.7.1.6 Any government requested delayed delivery up to 90 days after initial award delivery date, shall be at no additional cost to the Government. 2.7.1.7 A pre-delivery meeting will be conducted 60 days prior to initial award delivery date for verification of delivery and installation dates. 2.7.1.8 Delivery and Installation will be coordinated through the COR. 2.7.2 CONFIGURATION 2.7.2.1 All equipment shall be floor mounted by contractor upon delivery unless otherwise noted above. 2.7.2.2 Install/Configure all equipment to manufacturer s specifications maintaining Federal, and Local safety standards 2.7.2.3 Installation/Configuration must be completed by 31, 2018. All work shall be completed between 8:00 a.m. and 4:30 p.m. Monday Friday. All federal holidays, excluded. Federal holidays are available at the Federal Holiday OPM Site. 2.7.2.4 If there is an operational conflict with installation, night or weekend installation may be required. Government will provide a 72 hours' notice of change of installation hours. 2.7.2.5 The contractor shall coordinate all deliveries, staging areas, installations, and parking arrangements with the COR. 2.7.2.6 The Contractor shall remove all related shipping debris and cleanup any construction associated with delivery and installation of the specified items. Contractor shall remove all packaging from the SLVHCS premises. The Contractor shall be responsible for any damage to the building that occurs due to Contractor error or neglect. 2.8 SITE CONDITIONS 2.8.1 There shall be no smoking, eating, or drinking inside the hospital at any time. 3. INSPECTION AND ACCEPTANCE: 3.1 The Contractor shall conduct a joint inspection with the COR upon delivery of equipment. 3.2 Contractor shall provide dates of completion of punch list items and replacement parts and/or short ship items from the manufacturer(s). 3.3 The COR shall ensure all work is completed satisfactorily prior to acceptance. Disputes shall be resolved by the Contracting Officer. 4. DELIVERABLES 4.1 Operation and Maintenance Manuals 4.1.1 Binders - Quantity (1) set for each line item 4.1.2 Digital Copies- Quantity (1) each for item 4.2 Deliver compilation of all manufacturer recommended maintenance schedule and operation materials packaged in binder(s) to COR upon completion of installation. 5. OPERATOR TRAINING: 5.1 Contractor shall provide On-site training of the equipment to the Users. Scheduling of operator training shall be coordinated with the SLVHCS COR after installation is complete. 6. PROTECTION OF PROPERTY 6.1 Contractor shall protect all items from damage. The Contractor shall take precaution against damage to the building(s), grounds and furnishings. The Contractor shall repair or replace any items related to building(s) or grounds damaged accidentally or on purpose due to actions by the Contractor. 6.2 The Contractor shall perform an inspection of the building(s) and grounds with the COR prior to commencing work. To insure that the Contractor shall be able to repair or replace any items, components, building(s) or grounds damaged due to negligence and/or actions taken by the Contractor. The source of all repairs beyond simple surface cleaning is the facility construction contractor (or appropriate subcontractor), so that building warranty is maintained. Concurrence from the VA Facilities Management POC and COR is required before the Contractor may perform any significant repair work. In all cases, repairs shall utilize materials of the same quality, size, texture, grade, and color to match adjacent existing work. 6.3 The Contractor shall be responsible for security of the areas in which the work is being performed prior to completion. 6.4 Contractor shall provide floor protection while working in all VA facilities. All material handling equipment shall have rubber wheels. 7.1 The contractor shall provide a minimum one year manufacturer s warranty on all parts and labor. This warranty will begin upon opening of the SLVHCS Research building. 7.2 The warranty shall include all travel and shipping costs associated with any warranty repair. 8. SECURITY REQUIREMENTS 8.1 The Authorization & Accreditation (A&A) requirements do not apply and a Security Accreditation 8.2 See Attachment 1 (Att_1_PWS_ Security Requirements) for additional requirements.
- Web Link
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- Document(s)
- Attachment
- File Name: 36C25618Q9705 36C25618Q9705.docx (https://www.vendorportal.ecms.va.gov/FBODocumentServer/DocumentServer.aspx?DocumentId=4455616&FileName=36C25618Q9705-000.docx)
- Link: https://www.vendorportal.ecms.va.gov/FBODocumentServer/DocumentServer.aspx?DocumentId=4455616&FileName=36C25618Q9705-000.docx
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- File Name: 36C25618Q9705 36C25618Q9705.docx (https://www.vendorportal.ecms.va.gov/FBODocumentServer/DocumentServer.aspx?DocumentId=4455616&FileName=36C25618Q9705-000.docx)
- Place of Performance
- Address: Department of Veterans Affairs;Southeast Louisiana Veterans HCS;2400 Canal Street;New Orleans, La
- Zip Code: 70119
- Zip Code: 70119
- Record
- SN04975943-W 20180704/180702230609-1756e463e6521f67c8095a96947fba7b (fbodaily.com)
- Source
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