Loren Data's SAM Daily™

FBO DAILY - FEDBIZOPPS ISSUE OF MARCH 30, 2018 FBO #5971
SOURCES SOUGHT

66 -- Optogenetically Synchronized Fluorescence Microscope System - Technical Evaluation - Purchase Description

Notice Date

3/28/2018
 

Notice Type

Sources Sought
 

NAICS

333314 — Optical Instrument and Lens Manufacturing
 

Contracting Office

Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, 6001 Executive Boulevard, Room 4211, MSC 9559, Bethesda, Maryland, 20892-9559, United States
 

ZIP Code

20892-9559
 

Solicitation Number

NIHDA201800132
 

Archive Date

4/18/2018
 

Point of Contact

Stephanie D. Dewitt, Phone: 3014432848
 

E-Mail Address

stephanie.dewitt@nih.gov
(stephanie.dewitt@nih.gov)
 

Small Business Set-Aside

N/A
 

Description

Purchase Description Technical Evaluation The Integrative Neuroscience Branch conducts research at the cellular, molecular, and systems levels to identify the neural substrates upon which drugs of abuse act to produce long-term alterations in behavior and brain function. The Neuronal Networks Section (NNS) contributes to this research by delineating the afferent inputs, efferent targets, physiological characteristics, and behavioral functions of ventral tegmental area and dorsal raphe neurons. In order to accomplish this, they utilize classical tract tracing techniques, radioactive and nonradioactive in situ hybridization, ex vivo electrophysiological recordings, in vivo single-unit electrophysiological recordings, optogenetics, pharmacogenetics, and behavioral assays. NNS needs an optogenetically synchronized microscope system to synchronize optogenetic stimulation with deep brain calcium imaging of freely-moving animals like rats and mice. They have targets at -3.5 and -4.4 from the top of the skull and are working primarily with mice. The GCaMP6 + NpHR3.0 microscope version is needed for its compatibility with other red-shifted opsins like Chrimson and Breaches. See details in Purchase Description attached.
 

Web Link

FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDA-01/NIHDA201800132/listing.html)
 

Place of Performance

Address: 251 Bayview Blvd Suite 200, Baltimore, Maryland, 21224, United States

Zip Code: 21224
 

Record

SN04870389-W 20180330/180328231859-4e1ea2d694c08e93ea9f3e524b02e57b (fbodaily.com)
 

Source

FedBizOpps Link to This Notice
(may not be valid after Archive Date)

---

| FSG Index  |  This Issue's Index  |  Today's FBO Daily Index Page |