MODIFICATION
R -- Characterization and Quantification of Metabolites and Lipidomics Using Multiple Reaction Monitoring Mass Spectrometry (MRM-MS) as well Metabolomics/lipidomics Profiling Using Liquid Chromatography-mass Spectrometry (LC-MS) - Amendment 1
- Notice Date
- 3/23/2018
- Notice Type
- Modification/Amendment
- NAICS
- 541990
— All Other Professional, Scientific, and Technical Services
- Contracting Office
- Other Defense Agencies, Uniformed Services University of the Health Sciences, UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES (USUHS), 4301 JONES BRIDGE ROAD, Bethesda, Maryland, 20814-4799, United States
- ZIP Code
- 20814-4799
- Solicitation Number
- HU0001-18-Q-0005
- Archive Date
- 4/11/2018
- Point of Contact
- Christina Johnson, Phone: 3012953069, Melissa T. Beale, Phone: 3012953962
- E-Mail Address
-
christina.johnson@usuhs.edu, Melissa.Beale@usuhs.edu
(christina.johnson@usuhs.edu, Melissa.Beale@usuhs.edu)
- Small Business Set-Aside
- Total Small Business
- Description
- Copy of Amendment 0002 Amendment 0002 The purpose of this amendment is to address the following questions. 1. Estimated number of samples per year Government Response: Provided are the projected quantities for the three years. Quantities are estimates only. Regardless of the actual quantity ordered, the awardee must honor the unit price quoted. Line Item DESCRIPTION QUANTITYUNIT OF ISSUE Per SampleUNIT PRICE Per SampleTOTAL PRICE 0001Year 1: Mass Spectrometry based Metabolomics and Lipidomics Instrumental Analyses 250 0002Year 1: Mass Spectrometry based Metabolomics and Lipidomics Data Analyses 250 0003Year 2: Mass Spectrometry based Metabolomics and Lipidomics Instrumental Analyses 300 0004Year 2: Mass Spectrometry based Metabolomics and Lipidomics Data Analyses 300 0005Year 3: Mass Spectrometry based Metabolomics and Lipidomics Instrumental Analyses 400 0006Year 3: Mass Spectrometry based Metabolomics and Lipidomics Data Analyses 400 2. What type of samples (lungs, livers, urine, culture supernatants, plasma, serum, etc.,) (Mammal = Mice Vs Human) (Plants vs Animals) (microbes = mycobacteria?) (Virus?) Government's Response: Can be biofluids (plasma, serum, urine) and organs (any organ such as - heart, lung, kidney, jejunum, duodenum, bone marrow, liver etc.). Exact detail of sample will vary from study to study. 3. Lipidomics = Screening/non -targetted/global: What type of lipid class? They are several lipid classes (sphingolipids, ceramides, phospholipids, eicosanoids, fatty acids, and other neutral lipids) Government's Response: Global and all classes of lipids. 4. MRM = Targetted/Specific: Which lipid classes (as mentioned above) Government's Response: All classes of lipids 5. Analyses = Upto what stage, Lipid quantities or upto Biostat analyses to compare across various sample types i.e., e.g. diseased vs healthy? Government's Response: Up to biostat/bioinformatics, correlation with various category of samples, analysis to establish correlation with genders, treatment groups, enough support to make data publishable. Contractors must provide a statement of acknowledgement of Amendments 0001 and 0002. The response date for offers remains March 27, 2018 by 12:00 p.m. (EST).
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/notices/b8196141768c81e46042c2e0ac94b418)
- Place of Performance
- Address: 8401 Jones Bridge Road, Bethesda, Maryland, 20889, United States
- Zip Code: 20889
- Zip Code: 20889
- Record
- SN04865143-W 20180325/180323231257-b8196141768c81e46042c2e0ac94b418 (fbodaily.com)
- Source
-
FedBizOpps Link to This Notice
(may not be valid after Archive Date)
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