SOURCES SOUGHT
66 -- Light Sheet Microscopy System
- Notice Date
- 7/28/2017
- Notice Type
- Sources Sought
- NAICS
- 333314
— Optical Instrument and Lens Manufacturing
- Contracting Office
- Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, 6001 Executive Boulevard, Room 4211, MSC 9559, Bethesda, Maryland, 20892-9559, United States
- ZIP Code
- 20892-9559
- Solicitation Number
- HHS-NIH-NIDA-SSSA-SBSS-17-600
- Archive Date
- 8/22/2017
- Point of Contact
- Sneha V Singh, Phone: 3014802443
- E-Mail Address
-
sneha.singh@nih.gov
(sneha.singh@nih.gov)
- Small Business Set-Aside
- N/A
- Description
- Federal Business Opportunities (FBO) SOURCES SOUGHT NOTICE 1. Solicitation Number: HHS-NIH-NIDA-SSSA-SBSS-17-600 2. Title: Light Sheet Microscopy System 3. Classification Code: 6640 - Lab Equipment & Supplies 4. NAICS Code: 333314 - Optical Instrument and Lens Manufacturing 5. Description: This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources; (2) whether they are small businesses; HUBZone small businesses; service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. An organization that is not considered a small business under the applicable NAICS code should not submit a response to this notice. This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. Background: A National Institute of Mental Health (NIMH) lab seeks to understand how genetic and experiential factors impact the developmental trajectory and functional architecture of brain circuits critically involved in psychiatric disorders in order to develop improved treatment and management for these diseases. Among the core deficits associated with serious psychiatric disability, the impairment of executive function, affecting the planning, initiation and regulation of goal-directed behaviors, has been increasingly highlighted as of central importance. Normal executive function in goal-directed behavior depends on the frontal lobe, and functional brain imaging studies have revealed altered activities in this brain region in patients suffering from schizophrenia, depression and drug addiction. However, much less is known about the cellular and molecular mechanisms by which genetic and environmental factors perturb the development and function of frontal cortical circuits. Lack of such knowledge has hampered the identification of key cellular targets and molecular pathways for therapeutic interventions. The current focus of the Lab is to elucidate the basic cellular and molecular mechanisms underlying experience-dependent regulation of frontal cortical circuits in model organisms. Purpose and Objectives: The lab needs the ALPHA3 light sheet system addition to their existing Olympus microscope for rapidly imaging whole mouse brains. Light sheet imaging allows for rapid and efficient imaging of whole brains or thick sections. The Alpha3 system provides high performance light sheet imaging capabilities with ultra-thin optical sectioning and high speed acquisition for fixed or live samples. Project requirements: The lab will purchase the ALPHA3 system which includes: - laser combiner with 2 wavelengths - XY motorized stitching module - ALPHA3 Illumination unit - Z stage for volume scanning - 10x water Olympus dipping objective - Dichroics for detection unit - Chamber & Sample holder - Dualview module - QtSPIM software - Computer with monitor - Shipping,installation and training at NIH - 1 year warranty Anticipated period of performance: Within 60 days from date of award. The capability statement should include 1) the total number of employees, 2) documentation of ability to provide the required support, 3) any contractor GSA Schedule contracts by which all of the requirements may be met, if applicable, and 4) any other information considered relevant to this program such as: • respondents' opinions about the difficulty and/or feasibility of the potential requirement or proposed acquisition, possible solutions and approaches that may currently exist in the marketplace, and information regarding innovative ideas or concepts; • information regarding respondents': (a) staff expertise, including their availability, experience, and formal and other training; (b) current in-house capability and capacity to perform the work; (c) prior completed projects of similar nature; (d) corporate experience and management capability; and (e) examples of prior completed Government contracts, references, and other related information; The respondent must also provide their DUNS number, organization name, address, point of contact, and size and type of business (e.g., 8(a), HubZone, etc., pursuant to the applicable NAICS code and any other information that may be helpful in developing or finalizing the acquisition requirements. One (1) copy of the response is required and must be in Microsoft Word or Adobe PDF format using 11-point or 12-point font, 8-1/2" x 11" paper size, with 1" top, bottom, left and right margins, and with single or double spacing. The information submitted must be must be in and outline format that addresses each of the elements of the project requirement and in the capability statement /information sought paragraphs stated herein. A cover page and an executive summary may be included but is not required. The response is limited to ten (10) page limit. The 10-page limit does not include the cover page, executive summary, or references, if requested. The response must include the respondents' technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses. All responses to this notice must be submitted electronically to the Contract Specialists and Contracting Officer. Facsimile responses are NOT accepted. All capability statements sent in response to this Sources Sought Notice must be submitted to Sneha Singh, Contract Specialist, via email at sneha.singh@nih.gov before the closing date and time of this announcement. All responses must be received by the specified due date and time in order to be considered. Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a presolicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s)."
- Web Link
-
FBO.gov Permalink
(https://www.fbo.gov/spg/HHS/NIH/NIDA-01/HHS-NIH-NIDA-SSSA-SBSS-17-600/listing.html)
- Record
- SN04603491-W 20170730/170728232558-a925dd73dacf5d1291e0b8f8e36e0f2a (fbodaily.com)
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